uboot: (firmwareOdroidC2/C4) don't invoke patch tool, use patches = [] instead

https://github.com/NixOS/nixpkgs/blob/master/pkgs/stdenv/generic/setup.sh#L948 this can do it nicely. Signed-off-by: Anton Arapov <anton@deadbeef.mx>
2021-04-03 12:58:10 +02:00 · 2021-04-03 12:58:10 +02:00 · 56de2bcd43
commit 56de2bcd43
30691 changed files with 3076956 additions and 0 deletions
--- a/pkgs/applications/science/biology/EZminc/default.nix
+++ b/pkgs/applications/science/biology/EZminc/default.nix
@ -0,0 +1,30 @@
+{ lib, stdenv, fetchFromGitHub, cmake, pkg-config, libminc, bicpl, itk4, fftwFloat, gsl }:
+
+stdenv.mkDerivation rec {
+  pname = "EZminc";
+  version = "unstable-2019-03-12";
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "5e3333ee356f914d34d66d33ea8df809c7f7fa51";
+    sha256 = "0wy8cppf5xpgfqvgb3mqs1cjh81n6qzkk6zxv29wvng8nar9wsy4";
+  };
+
+  nativeBuildInputs = [ cmake pkg-config ];
+  buildInputs = [ itk4 libminc bicpl fftwFloat gsl ];
+
+  cmakeFlags = [ "-DLIBMINC_DIR=${libminc}/lib/cmake"
+                 "-DEZMINC_BUILD_TOOLS=TRUE"
+                 "-DEZMINC_BUILD_MRFSEG=TRUE"
+                 "-DEZMINC_BUILD_DD=TRUE" ];
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/${pname}";
+    description = "Collection of Perl and shell scripts for processing MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license = licenses.free;
+    broken = true;  # ITK5 compatibility issue (https://github.com/BIC-MNI/EZminc/issues/15)
+  };
+}
--- a/pkgs/applications/science/biology/MACS2/default.nix
+++ b/pkgs/applications/science/biology/MACS2/default.nix
@ -0,0 +1,25 @@
+{ lib, python3, fetchurl }:
+
+python3.pkgs.buildPythonPackage rec {
+  pname = "MACS2";
+  version = "2.2.7.1";
+
+  src = python3.pkgs.fetchPypi {
+    inherit pname version;
+    sha256 = "1rcxj943kgzs746f5jrb72x1cp4v50rk3qmad0m99a02vndscb5d";
+  };
+
+  propagatedBuildInputs = with python3.pkgs; [ numpy ];
+
+  # To prevent ERROR: diffpeak_cmd (unittest.loader._FailedTest) for obsolete
+  # function (ImportError: Failed to import test module: diffpeak_cmd)
+  doCheck = false;
+  pythonImportsCheck = [ "MACS2" ];
+
+  meta = with lib; {
+    description = "Model-based Analysis for ChIP-Seq";
+    license = licenses.bsd3;
+    maintainers = with maintainers; [ gschwartz ];
+    platforms = platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/N3/default.nix
+++ b/pkgs/applications/science/biology/N3/default.nix
@ -0,0 +1,35 @@
+{ lib, stdenv, fetchFromGitHub, cmake, makeWrapper,
+  perlPackages,
+  libminc, EBTKS }:
+
+stdenv.mkDerivation rec {
+  pname = "N3";
+  version = "unstable-2018-08-09";
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "010fc2ac58ce1d67b8e6a863fac0809d3203cb9b";
+    sha256 = "06hci7gzhy8p34ggvx7gah2k9yxpwhgmq1cgw8pcd1r82g4rg6kd";
+  };
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ libminc EBTKS ];
+  propagatedBuildInputs = with perlPackages; [ perl MNI-Perllib GetoptTabular ];
+
+  cmakeFlags = [ "-DLIBMINC_DIR=${libminc}/lib/cmake" "-DEBTKS_DIR=${EBTKS}/lib/" ];
+
+  postFixup = ''
+    for p in $out/bin/*; do
+      wrapProgram $p --prefix PERL5LIB : $PERL5LIB
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/N3";
+    description = "MRI non-uniformity correction for MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license   = licenses.free;
+  };
+}
--- a/pkgs/applications/science/biology/angsd/default.nix
+++ b/pkgs/applications/science/biology/angsd/default.nix
@ -0,0 +1,25 @@
+{ lib, stdenv, fetchFromGitHub, htslib, zlib, bzip2, xz, curl, openssl }:
+
+stdenv.mkDerivation rec {
+  pname = "angsd";
+  version = "0.937";
+
+  src = fetchFromGitHub {
+    owner = "ANGSD";
+    repo = "angsd";
+    sha256 = "1020gh066dprqhfi90ywqzqqnq7awn49wrkkjnizmmab52v00kxs";
+    rev = "${version}";
+  };
+
+  buildInputs = [ htslib zlib bzip2 xz curl openssl ];
+
+  makeFlags = [ "HTSSRC=systemwide" "prefix=$(out)" ];
+
+  meta = with lib; {
+    description = "Program for analysing NGS data";
+    homepage = "http://www.popgen.dk/angsd";
+    maintainers = [ maintainers.bzizou ];
+    license = licenses.gpl2;
+  };
+}
+
--- a/pkgs/applications/science/biology/ants/default.nix
+++ b/pkgs/applications/science/biology/ants/default.nix
@ -0,0 +1,40 @@
+{ lib, stdenv, fetchFromGitHub, fetchpatch, cmake, makeWrapper, itk4, vtk_7, Cocoa }:
+
+stdenv.mkDerivation rec {
+  pname    = "ANTs";
+  version = "2.2.0";
+
+  src = fetchFromGitHub {
+    owner  = "ANTsX";
+    repo   = "ANTs";
+    rev    = "37ad4e20be3a5ecd26c2e4e41b49e778a0246c3d";
+    sha256 = "1hrdwv3m9xh3yf7l0rm2ggxc2xzckfb8srs88g485ibfszx7i03q";
+  };
+
+  patches = [
+    # Fix build with gcc8
+    (fetchpatch {
+      url = "https://github.com/ANTsX/ANTs/commit/89af9b2694715bf8204993e032fa132f80cf37bd.patch";
+      sha256 = "1glkrwa1jmxxbmzihycxr576azjqby31jwpj165qc54c91pn0ams";
+    })
+  ];
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ itk4 vtk_7 ] ++ lib.optionals stdenv.isDarwin [ Cocoa ];
+
+  cmakeFlags = [ "-DANTS_SUPERBUILD=FALSE" "-DUSE_VTK=TRUE" ];
+
+  postInstall = ''
+    for file in $out/bin/*; do
+      wrapProgram $file --set ANTSPATH "$out/bin"
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/ANTsX/ANTs";
+    description = "Advanced normalization toolkit for medical image registration and other processing";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license = licenses.bsd3;
+  };
+}
--- a/pkgs/applications/science/biology/aragorn/default.nix
+++ b/pkgs/applications/science/biology/aragorn/default.nix
@ -0,0 +1,28 @@
+{ lib, stdenv, fetchurl }:
+
+stdenv.mkDerivation rec {
+  version = "1.2.38";
+  pname = "aragorn";
+
+  src = fetchurl {
+    url = "http://mbio-serv2.mbioekol.lu.se/ARAGORN/Downloads/${pname}${version}.tgz";
+    sha256 = "09i1rg716smlbnixfm7q1ml2mfpaa2fpn3hwjg625ysmfwwy712b";
+  };
+
+  buildPhase = ''
+    $CC -O3 -ffast-math -finline-functions -o aragorn aragorn${version}.c
+  '';
+
+  installPhase = ''
+    mkdir -p $out/bin && cp aragorn $out/bin
+    mkdir -p $out/man/1 && cp aragorn.1 $out/man/1
+  '';
+
+  meta = with lib; {
+    description = "Detects tRNA, mtRNA, and tmRNA genes in nucleotide sequences";
+    homepage = "http://mbio-serv2.mbioekol.lu.se/ARAGORN/";
+    license = licenses.gpl2;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/astral/default.nix
+++ b/pkgs/applications/science/biology/astral/default.nix
@ -0,0 +1,60 @@
+{ lib
+, stdenvNoCC
+, fetchFromGitHub
+, jdk8
+, makeWrapper
+, jre8
+, zip
+}:
+let
+  jdk = jdk8;
+  jre = jre8;
+in
+stdenvNoCC.mkDerivation rec {
+  pname = "astral";
+  version = "5.7.1";
+
+  src = fetchFromGitHub {
+    owner = "smirarab";
+    repo = "ASTRAL";
+    rev = "v${version}";
+    sha256 = "043w2z6gbrisqirdid022f4b8jps1pp5syi344krv2bis1gjq5sn";
+  };
+
+  nativeBuildInputs = [ jdk makeWrapper jre zip ];
+
+  buildPhase = ''
+    patchShebangs ./make.sh
+    ./make.sh
+  '';
+
+  doCheck = true;
+
+  checkPhase = ''
+    runHook preCheck
+    java -jar astral.${version}.jar -i main/test_data/song_primates.424.gene.tre
+    runHook postCheck
+  '';
+
+  installPhase = ''
+    mkdir -p $out/share/lib
+    mkdir -p $out/bin
+    mv astral.${version}.jar $out/share/
+    mv lib/*.jar $out/share/lib
+    mv Astral.${version}.zip $out/share/
+    cp -a  main/test_data $out/share/
+    makeWrapper ${jre}/bin/java $out/bin/astral \
+        --add-flags "-jar $out/share/astral.${version}.jar"
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/smirarab/ASTRAL";
+    description = "Tool for estimating an unrooted species tree given a set of unrooted gene trees";
+    sourceProvenance = with sourceTypes; [
+      fromSource
+      binaryBytecode  # source bundles dependencies as jars
+    ];
+    license = licenses.asl20;
+    maintainers = with maintainers; [ bzizou ];
+  };
+}
--- a/pkgs/applications/science/biology/bayescan/default.nix
+++ b/pkgs/applications/science/biology/bayescan/default.nix
@ -0,0 +1,42 @@
+{ lib, stdenv, fetchurl, unzip, llvmPackages }:
+
+stdenv.mkDerivation rec {
+  pname = "bayescan";
+  version = "2.1";
+
+  src = fetchurl {
+    url = "http://cmpg.unibe.ch/software/BayeScan/files/BayeScan${version}.zip";
+    sha256 = "0ismima8j8z0zj9yc267rpf7z90w57b2pbqzjnayhc3ab8mcbfy6";
+  };
+
+  nativeBuildInputs = [ unzip ];
+  buildInputs = lib.optional stdenv.cc.isClang llvmPackages.openmp;
+
+  # Disable FORTIFY_SOURCE or the binary fails with "buffer overflow"
+  hardeningDisable = [ "fortify" ];
+
+  sourceRoot = "BayeScan${version}/source";
+
+  postPatch = ''
+    substituteInPlace Makefile --replace "-static" "" \
+                               --replace "g++" "c++"
+  '';
+
+  installPhase = ''
+    mkdir -p $out/bin
+    mkdir -p $out/share/doc/bayescan
+    cp bayescan_${version} $out/bin
+    cp -r ../*pdf ../input_examples ../"R functions" $out/share/doc/bayescan
+  '';
+
+  NIX_CFLAGS_COMPILE = [ "-std=c++14" ];
+
+  meta = with lib; {
+    description = "Detecting natural selection from population-based genetic data";
+    homepage = "http://cmpg.unibe.ch/software/BayeScan";
+    license = licenses.gpl3;
+    maintainers = [ maintainers.bzizou ];
+    mainProgram = "bayescan_${version}";
+    platforms = lib.platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/bcftools/default.nix
+++ b/pkgs/applications/science/biology/bcftools/default.nix
@ -0,0 +1,44 @@
+{ lib, stdenv, fetchurl, htslib, zlib, bzip2, xz, curl, perl, python3, bash }:
+
+stdenv.mkDerivation rec {
+  pname = "bcftools";
+  version = "1.15";
+
+  src = fetchurl {
+    url = "https://github.com/samtools/bcftools/releases/download/${version}/${pname}-${version}.tar.bz2";
+    sha256 = "sha256-GIXMtFCobpegCqkF1zgcqeB72JZ8BXBaYdAAfS4iKW4=";
+  };
+
+  nativeBuildInputs = [
+    perl
+    python3
+  ];
+
+  buildInputs = [ htslib zlib bzip2 xz curl ];
+
+  strictDeps = true;
+
+  makeFlags = [
+    "HSTDIR=${htslib}"
+    "prefix=$(out)"
+    "CC=${stdenv.cc.targetPrefix}cc"
+  ];
+
+  preCheck = ''
+    patchShebangs misc/
+    patchShebangs test/
+    sed -ie 's|/bin/bash|${bash}/bin/bash|' test/test.pl
+  '';
+
+  enableParallelBuilding = true;
+
+  doCheck = true;
+
+  meta = with lib; {
+    description = "Tools for manipulating BCF2/VCF/gVCF format, SNP and short indel sequence variants";
+    license = licenses.mit;
+    homepage = "http://www.htslib.org/";
+    platforms = platforms.unix;
+    maintainers = [ maintainers.mimame ];
+  };
+}
--- a/pkgs/applications/science/biology/bedops/default.nix
+++ b/pkgs/applications/science/biology/bedops/default.nix
@ -0,0 +1,51 @@
+{ lib, stdenv, fetchFromGitHub, zlib, bzip2, jansson, makeWrapper }:
+
+stdenv.mkDerivation rec {
+  pname = "bedops";
+  version = "2.4.40";
+
+  src = fetchFromGitHub {
+    owner = "bedops";
+    repo = "bedops";
+    rev = "v${version}";
+    sha256 = "sha256-rJVl3KbzGblyQZ7FtJXeEv/wjQJmzYGNjzhvkoMoBWY=";
+  };
+
+  buildInputs = [ zlib bzip2 jansson ];
+  nativeBuildInputs = [ makeWrapper ];
+
+  preConfigure = ''
+    # We use nixpkgs versions of these libraries
+    rm -r third-party
+    sed -i '/^LIBS/d' system.mk/*
+    sed -i 's|^LIBRARIES.*$|LIBRARIES = -lbz2 -lz -ljansson|' */*/*/*/Makefile
+    substituteInPlace applications/bed/starch/src/Makefile --replace '$(LIBRARIES)' ""
+
+    # Function name is different in nixpkgs provided libraries
+    for f in interfaces/src/data/starch/starchFileHelpers.c applications/bed/starch/src/starchcat.c ; do
+      substituteInPlace $f --replace deflateInit2cpp deflateInit2
+    done
+
+    # Don't force static
+    for f in */*/*/*/Makefile ; do
+      substituteInPlace $f --replace '-static' ""
+    done
+  '';
+
+  makeFlags = [ "BINDIR=$(out)/bin" ];
+
+  postFixup = ''
+    for f in $out/bin/* ; do
+      wrapProgram $f --prefix PATH : "$out/bin"
+    done
+  '';
+
+  meta = with lib; {
+    description = "Suite of tools for addressing questions arising in genomics studies";
+    homepage = "https://github.com/bedops/bedops";
+    license = licenses.gpl2Only;
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.x86_64;
+    broken = stdenv.isDarwin;
+  };
+}
--- a/pkgs/applications/science/biology/bedtools/default.nix
+++ b/pkgs/applications/science/biology/bedtools/default.nix
@ -0,0 +1,34 @@
+{lib, stdenv, fetchFromGitHub, zlib, python3, bzip2, xz}:
+
+stdenv.mkDerivation rec {
+  pname = "bedtools";
+  version = "2.30.0";
+
+  src = fetchFromGitHub {
+    owner = "arq5x";
+    repo = "bedtools2";
+    rev = "v${version}";
+    sha256 = "sha256-NqKldF7ePJn3pT+AkESIQghBKSFFOEBBsTaKEbU+oaQ=";
+  };
+
+  strictDeps = true;
+
+  nativeBuildInputs = [
+    python3
+  ];
+
+  buildInputs = [ zlib bzip2 xz ];
+
+  cxx = if stdenv.cc.isClang then "clang++" else "g++";
+  cc = if stdenv.cc.isClang then "clang" else "gcc";
+  buildPhase = "make prefix=$out SHELL=${stdenv.shell} CXX=${cxx} CC=${cc} -j $NIX_BUILD_CORES";
+  installPhase = "make prefix=$out SHELL=${stdenv.shell} CXX=${cxx} CC=${cc} install";
+
+  meta = with lib; {
+    description = "A powerful toolset for genome arithmetic";
+    license = licenses.gpl2;
+    homepage = "https://bedtools.readthedocs.io/en/latest/";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/bftools/default.nix
+++ b/pkgs/applications/science/biology/bftools/default.nix
@ -0,0 +1,42 @@
+{ stdenv, lib, makeWrapper, fetchzip, jre }:
+
+stdenv.mkDerivation rec {
+  pname = "bftools";
+  version = "6.3.0";
+
+  src = fetchzip {
+    url = "http://downloads.openmicroscopy.org/bio-formats/${version}/artifacts/bftools.zip";
+    sha256 = "02nvvmpfglpah1ihd08aw65g1794w588c988cdar1hfl4s80qwhb";
+  };
+
+  installPhase = ''
+    find . -maxdepth 1 -perm -111 -type f -not -name "*.sh" \
+      -exec install -vD {} "$out"/bin/{} \;
+
+    mkdir $out/libexec
+    mkdir -p $out/share/java
+
+    cp ./*.sh $out/libexec
+    cp ./*.jar $out/share/java
+
+    for file in $out/bin/*; do
+      substituteInPlace $file --replace "\$BF_DIR" $out/libexec
+    done
+    substituteInPlace $out/libexec/bf.sh --replace "\$BF_JAR_DIR" $out/share/java
+  '';
+
+  postFixup = ''
+    wrapProgram $out/libexec/bf.sh --prefix PATH : "${lib.makeBinPath [ jre ]}"
+  '';
+
+  nativeBuildInputs = [ makeWrapper ];
+
+  meta = with lib; {
+    description = "A bundle of scripts for using Bio-Formats on the command line with bioformats_package.jar already included";
+    sourceProvenance = with sourceTypes; [ binaryBytecode ];
+    license = licenses.gpl2;
+    platforms = platforms.all;
+    homepage = "https://www.openmicroscopy.org/bio-formats/";
+    maintainers = [ maintainers.tbenst ];
+  };
+}
--- a/pkgs/applications/science/biology/blast/default.nix
+++ b/pkgs/applications/science/biology/blast/default.nix
@ -0,0 +1,109 @@
+{ lib, stdenv, buildPackages, fetchurl, zlib, bzip2, perl, cpio, gawk, coreutils, ApplicationServices }:
+
+stdenv.mkDerivation rec {
+  pname = "blast";
+  version = "2.13.0";
+
+  src = fetchurl {
+    url = "https://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/${version}/ncbi-blast-${version}+-src.tar.gz";
+    sha256 = "sha256-iVU3FNEz2vKMR3+D0zN5Szxi5BSECMByobRiDl7E/rI=";
+  };
+
+  sourceRoot = "ncbi-blast-${version}+-src/c++";
+
+  configureFlags = [
+    # With flat Makefile we can use all_projects in order not to build extra.
+    # These extra cause clang to hang on Darwin.
+    "--with-flat-makefile"
+    "--without-makefile-auto-update"
+    "--with-dll"  # build dynamic libraries (static are default)
+    ];
+
+  makeFlags = [ "all_projects=app/" ];
+
+  preConfigure = ''
+    export NCBICXX_RECONF_POLICY=warn
+    export PWD=$(pwd)
+    export HOME=$PWD
+
+    # The configure scripts wants to set AR="ar cr" unless it is already set in
+    # the environment. Because stdenv sets AR="ar", the result is a bad call to
+    # the assembler later in the process. Thus, we need to unset AR
+    unset AR
+
+    for awks in scripts/common/impl/is_log_interesting.awk \
+        scripts/common/impl/report_duplicates.awk; do
+
+        substituteInPlace $awks \
+              --replace /usr/bin/awk ${gawk}/bin/awk
+    done
+
+    for mk in src/build-system/Makefile.meta.in \
+        src/build-system/helpers/run_with_lock.c ; do
+
+        substituteInPlace $mk \
+        --replace /bin/rm ${coreutils}/bin/rm
+    done
+
+    for mk in src/build-system/Makefile.meta.gmake=no \
+        src/build-system/Makefile.meta_l \
+        src/build-system/Makefile.meta_r \
+        src/build-system/Makefile.requirements \
+        src/build-system/Makefile.rules_with_autodep.in; do
+
+        substituteInPlace $mk \
+            --replace /bin/echo ${coreutils}/bin/echo
+    done
+    for mk in src/build-system/Makefile.meta_p \
+        src/build-system/Makefile.rules_with_autodep.in \
+        src/build-system/Makefile.protobuf.in ; do
+
+        substituteInPlace $mk \
+            --replace /bin/mv ${coreutils}/bin/mv
+    done
+
+
+    substituteInPlace src/build-system/configure \
+        --replace /bin/pwd ${coreutils}/bin/pwd \
+        --replace /bin/ln ${coreutils}/bin/ln
+
+    substituteInPlace src/build-system/configure.ac \
+        --replace /bin/pwd ${coreutils}/bin/pwd \
+        --replace /bin/ln ${coreutils}/bin/ln
+
+    substituteInPlace src/build-system/Makefile.meta_l \
+        --replace /bin/date ${coreutils}/bin/date
+  '';
+
+  depsBuildBuild = [ buildPackages.stdenv.cc ];
+  nativeBuildInputs = [ perl ];
+
+  # perl is necessary in buildInputs so that installed perl scripts get patched
+  # correctly
+  buildInputs = [ coreutils perl gawk zlib bzip2 cpio ]
+    ++ lib.optionals stdenv.isDarwin [ ApplicationServices ];
+  hardeningDisable = [ "format" ];
+
+  postInstall = ''
+    substituteInPlace $out/bin/get_species_taxids.sh \
+        --replace /bin/rm ${coreutils}/bin/rm
+  '';
+  patches = [ ./no_slash_bin.patch ];
+
+  enableParallelBuilding = true;
+
+  # Many tests require either network access or locally available databases
+  doCheck = false;
+
+  meta = with lib; {
+    description = ''Basic Local Alignment Search Tool (BLAST) finds regions of
+    similarity between biological sequences'';
+    homepage = "https://blast.ncbi.nlm.nih.gov/Blast.cgi";
+    license = licenses.publicDomain;
+
+    # Version 2.10.0 fails on Darwin
+    # See https://github.com/NixOS/nixpkgs/pull/61430
+    platforms = platforms.linux;
+    maintainers = with maintainers; [ luispedro ];
+  };
+}
--- a/pkgs/applications/science/biology/blast/no_slash_bin.patch
+++ b/pkgs/applications/science/biology/blast/no_slash_bin.patch
@ -0,0 +1,178 @@
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/collect_outside_libs.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/collect_outside_libs.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/collect_outside_libs.sh	2014-08-01 22:01:17.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/collect_outside_libs.sh	2019-05-15 12:40:44.145239480 +0800
+@@ -1,8 +1,5 @@
+ #!/bin/sh
+ set -e
+-PATH=/bin:/usr/bin
+-export PATH
+-unset CDPATH
+ 
+ base=$1
+ search=`echo ${2-$LD_LIBRARY_PATH} | tr : ' '`
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/create_flat_tuneups.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/create_flat_tuneups.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/create_flat_tuneups.sh	2011-08-17 02:55:10.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/create_flat_tuneups.sh	2019-05-15 12:40:48.449276574 +0800
+@@ -1,9 +1,6 @@
+ #!/bin/sh
+ id='$Id: create_flat_tuneups.sh 331412 2011-08-16 18:55:10Z ucko $'
+ 
+-PATH=/bin:/usr/bin
+-export PATH
+-
+ exec > auto_flat_tuneups.mk
+ 
+ cat <<EOF
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/get_lock.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/get_lock.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/get_lock.sh	2011-08-20 04:12:28.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/get_lock.sh	2019-05-15 12:40:52.901315000 +0800
+@@ -1,7 +1,5 @@
+ #!/bin/sh
+ 
+-PATH=/bin:/usr/bin
+-export PATH
+ 
+ dir=$1.lock
+ 
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/if_diff.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/if_diff.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/if_diff.sh	2014-07-30 22:06:45.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/if_diff.sh	2019-05-15 12:42:57.298410841 +0800
+@@ -4,9 +4,6 @@
+ # Author:  Denis Vakatov (vakatov@ncbi.nlm.nih.gov)
+ #################################
+ 
+-orig_PATH=$PATH
+-PATH=/bin:/usr/bin
+-
+ script_name=`basename $0`
+ script_args="$*"
+ 
+@@ -16,7 +13,7 @@
+ base_action=`basename "$action"`
+ case "$base_action" in
+   cp | cp\ * | ln | ln\ * )
+-      action=/bin/$base_action
+      action=$base_action
+       rm="rm -f"
+       ;;
+   * )
+@@ -58,10 +55,8 @@
+   shift
+   cmd="$* $dest_file"
+   test "$quiet" = yes || echo "$cmd"
+-  PATH=$orig_PATH
+   "$@" "$dest"
+   status=$?
+-  PATH=/bin:/usr/bin
+   return $status
+ }
+ 
+@@ -74,7 +69,7 @@
+   case "$base_action" in
+     ln | ln\ -f )
+       test "$quiet" = yes || echo "failed; trying \"cp -p ...\" instead"
+-      cmd="/bin/cp -p $src_file $dest_file"
+      cmd="cp -p $src_file $dest_file"
+       ExecHelper "$dest_file" /bin/cp -p "$src_file"  ||
+       Usage "\"$cmd\" failed"
+       ;;
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/make_lock_map.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/make_lock_map.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/make_lock_map.sh	2011-11-17 04:43:52.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/make_lock_map.sh	2019-05-15 12:40:56.769348434 +0800
+@@ -1,8 +1,6 @@
+ #!/bin/sh
+ # $Id: make_lock_map.sh 344587 2011-11-16 20:43:52Z ucko $
+ 
+-PATH=/bin:/usr/bin
+-export PATH
+ 
+ act=false
+ cache_dir='.#SRC-cache'
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/run_with_lock.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/run_with_lock.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/run_with_lock.sh	2015-10-29 22:36:05.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/run_with_lock.sh	2019-05-15 12:41:53.401842849 +0800
+@@ -1,10 +1,6 @@
+ #!/bin/sh
+ # $Id: run_with_lock.sh 483249 2015-10-29 14:36:05Z ucko $
+ 
+-orig_PATH=$PATH
+-PATH=/bin:/usr/bin
+-export PATH
+-
+ base=
+ logfile=
+ map=
+@@ -23,7 +19,7 @@
+ : ${base:=`basename "$1"`}
+ 
+ clean_up () {
+-    /bin/rm -rf "$base.lock"
+    rm -rf "$base.lock"
+ }
+ 
+ case $0 in
+@@ -45,7 +41,7 @@
+     trap "clean_up; exit $error_status" 1 2 15
+     if [ -n "$logfile" ]; then
+         status_file=$base.lock/status
+-        (PATH=$orig_PATH; export PATH; "$@"; echo $? > "$status_file") 2>&1 \
+        ("$@"; echo $? > "$status_file") 2>&1 \
+             | tee "$logfile.new"
+         # Emulate egrep -q to avoid having to move from under scripts.
+         if [ ! -f "$logfile" ]  \
+@@ -58,8 +54,6 @@
+             status=1
+         fi
+     else
+-        PATH=$orig_PATH
+-        export PATH
+         "$@"
+         status=$?
+     fi
+diff -u --recursive ncbi-blast-2.9.0+-src/scripts/common/impl/strip_for_install.sh ncbi-blast-2.9.0+-src.patched/scripts/common/impl/strip_for_install.sh
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/strip_for_install.sh	2013-09-24 03:06:51.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/strip_for_install.sh	2019-05-15 12:40:13.272975092 +0800
+@@ -1,8 +1,5 @@
+ #!/bin/sh
+ 
+-PATH=/bin:/usr/bin:/usr/ccs/bin
+-export PATH
+-
+ case "$1" in
+     --dirs )
+         shift
+--- ncbi-blast-2.9.0+-src/scripts/common/impl/update_configurable.sh	2017-07-13 22:53:24.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/scripts/common/impl/update_configurable.sh	2019-05-15 15:03:35.861276083 +0800
+@@ -1,6 +1,4 @@
+ #!/bin/sh
+-PATH=/bin:/usr/bin
+-export PATH
+ 
+ script_name=`basename $0`
+ script_dir=`dirname $0`
+--- ncbi-blast-2.9.0+-src/src/build-system/Makefile.mk.in	2019-01-04 01:38:37.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/src/build-system/Makefile.mk.in	2019-05-15 15:14:41.749416495 +0800
+@@ -50,12 +50,12 @@
+ 
+ ### Auxiliary commands, filters
+ 
+-RM       = /bin/rm -f
+-RMDIR    = /bin/rm -rf
+-COPY     = /bin/cp -p
+RM       = rm -f
+RMDIR    = rm -rf
+COPY     = cp -p
+ BINCOPY  = @BINCOPY@
+ TOUCH    = @TOUCH@
+-MKDIR    = /bin/mkdir
+MKDIR    = mkdir
+ BINTOUCH = $(TOUCH)
+ LN_S     = @LN_S@
+ GREP     = @GREP@
+--- ncbi-blast-2.9.0+-src/src/build-system/configure	2019-03-05 00:49:08.000000000 +0800
+++ ncbi-blast-2.9.0+-src.patched/src/build-system/configure	2019-05-15 16:55:40.711795042 +0800
+@@ -10417,4 +10417,0 @@
+-case "$LN_S" in
+-    /*) ;;
+-    * ) LN_S=/bin/$LN_S ;;
+-esac
--- a/pkgs/applications/science/biology/bowtie/default.nix
+++ b/pkgs/applications/science/biology/bowtie/default.nix
@ -0,0 +1,45 @@
+{ lib, stdenv, fetchFromGitHub, fetchpatch, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "bowtie";
+  version = "1.3.1";
+
+  src = fetchFromGitHub {
+    owner = "BenLangmead";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "sha256-mWItmrTMPst/NnzSpxxTHcBztDqHPCza9yOsZPwp7G4=";
+  };
+
+  patches = [
+    # Without this patch, compiling with clang on an M1 Mac fails because
+    # 'cpuid.h' is included. It only works on x86 and throws an error.
+    (fetchpatch {
+      name = "fix_compilation_on_arm64";
+      url = "https://github.com/BenLangmead/bowtie/commit/091d72f4cb69ca0713704d38bd7f9b37e6c4ff2d.patch";
+      sha256 = "sha256-XBvgICUBnE5HKpJ36IHTDiKjJgLFKETsIaJC46uN+2I=";
+    })
+
+    # Without this patch, compilation adds the current source directory to the
+    # include search path, and #include <version> in standard library code can
+    # end up picking the unrelated VERSION source code file on case-insensitive
+    # file systems.
+    (fetchpatch {
+      name = "fix_include_search_path";
+      url = "https://github.com/BenLangmead/bowtie/commit/c208b9db936eab0bc3ffdf0182b4f59a9017a1c4.patch";
+      sha256 = "sha256-772EE+oWFWXssSMabPryb0AfIS1tC10mPTRCBm7RrUs=";
+    })
+  ];
+
+  buildInputs = [ zlib ];
+
+  installFlags = [ "prefix=$(out)" ];
+
+  meta = with lib; {
+    description = "An ultrafast memory-efficient short read aligner";
+    license = licenses.artistic2;
+    homepage = "http://bowtie-bio.sourceforge.net";
+    maintainers = with maintainers; [ prusnak ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/bowtie2/default.nix
+++ b/pkgs/applications/science/biology/bowtie2/default.nix
@ -0,0 +1,26 @@
+{ lib, stdenv, fetchFromGitHub, cmake, tbb, zlib, python3, perl }:
+
+stdenv.mkDerivation rec {
+  pname = "bowtie2";
+  version = "2.4.5";
+
+  src = fetchFromGitHub {
+    owner = "BenLangmead";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "sha256-xCsTkQXrZS+Njn0YfidhPln+OwVfTXOqbtB0dCfTP2U=";
+  };
+
+  nativeBuildInputs = [ cmake ];
+
+  buildInputs = [ tbb zlib python3 perl ];
+
+  meta = with lib; {
+    description = "An ultrafast and memory-efficient tool for aligning sequencing reads to long reference sequences";
+    license = licenses.gpl3;
+    homepage = "http://bowtie-bio.sf.net/bowtie2";
+    maintainers = with maintainers; [ rybern ];
+    platforms = platforms.all;
+    broken = stdenv.isAarch64; # only x86 is supported
+  };
+}
--- a/pkgs/applications/science/biology/bppsuite/default.nix
+++ b/pkgs/applications/science/biology/bppsuite/default.nix
@ -0,0 +1,21 @@
+{ stdenv, fetchFromGitHub, cmake, bpp-core, bpp-seq, bpp-phyl, bpp-popgen }:
+
+stdenv.mkDerivation rec {
+  pname = "bppsuite";
+
+  inherit (bpp-core) version;
+
+  src = fetchFromGitHub {
+    owner = "BioPP";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "1wdwcgczqbc3m116vakvi0129wm3acln3cfc7ivqnalwvi6lrpds";
+  };
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ bpp-core bpp-seq bpp-phyl bpp-popgen ];
+
+  meta = bpp-core.meta // {
+    changelog = "https://github.com/BioPP/bppsuite/blob/master/ChangeLog";
+  };
+}
--- a/pkgs/applications/science/biology/bwa/default.nix
+++ b/pkgs/applications/science/biology/bwa/default.nix
@ -0,0 +1,50 @@
+{ lib, stdenv, fetchurl, fetchpatch, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "bwa";
+  version = "0.7.17";
+
+  src = fetchurl {
+    url = "mirror://sourceforge/bio-bwa/${pname}-${version}.tar.bz2";
+    sha256 = "1zfhv2zg9v1icdlq4p9ssc8k01mca5d1bd87w71py2swfi74s6yy";
+  };
+
+  patches = [
+    # Pull upstream patch for -fno-common toolchain support like upstream
+    # gcc-10: https://github.com/lh3/bwa/pull/267
+    (fetchpatch {
+      name  = "fno-common.patch";
+      url = "https://github.com/lh3/bwa/commit/2a1ae7b6f34a96ea25be007ac9d91e57e9d32284.patch";
+      sha256 = "1lihfxai6vcshv5vr3m7yhk833bdivkja3gld6ilwrc4z28f6wqy";
+    })
+  ];
+
+  buildInputs = [ zlib ];
+
+  # Avoid hardcoding gcc to allow environments with a different
+  # C compiler to build
+  preConfigure = ''
+    sed -i '/^CC/d' Makefile
+  '';
+
+  makeFlags = lib.optional stdenv.hostPlatform.isStatic "AR=${stdenv.cc.targetPrefix}ar";
+
+  # it's unclear which headers are intended to be part of the public interface
+  # so we may find ourselves having to add more here over time
+  installPhase = ''
+    install -vD -t $out/bin bwa
+    install -vD -t $out/lib libbwa.a
+    install -vD -t $out/include bntseq.h
+    install -vD -t $out/include bwa.h
+    install -vD -t $out/include bwamem.h
+    install -vD -t $out/include bwt.h
+  '';
+
+  meta = with lib; {
+    description = "A software package for mapping low-divergent sequences against a large reference genome, such as the human genome";
+    license     = licenses.gpl3;
+    homepage    = "http://bio-bwa.sourceforge.net/";
+    maintainers = with maintainers; [ luispedro ];
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/cd-hit/default.nix
+++ b/pkgs/applications/science/biology/cd-hit/default.nix
@ -0,0 +1,38 @@
+{ lib, stdenv, fetchFromGitHub, makeWrapper, zlib, perl, perlPackages, openmp }:
+
+stdenv.mkDerivation rec {
+  version = "4.8.1";
+  pname = "cd-hit";
+
+  src = fetchFromGitHub {
+    owner = "weizhongli";
+    repo = "cdhit";
+    rev = "V${version}";
+    sha256 = "032nva6iiwmw59gjipm1mv0xlcckhxsf45mc2qbnv19lbis0q22i";
+  };
+
+  propagatedBuildInputs = [ perl perlPackages.TextNSP perlPackages.ImageMagick ];
+
+  nativeBuildInputs = [ zlib makeWrapper ];
+  buildInputs = lib.optional stdenv.cc.isClang openmp;
+
+  makeFlags = [
+    "CC=${stdenv.cc.targetPrefix}c++" # remove once https://github.com/weizhongli/cdhit/pull/114 is merged
+    "PREFIX=$(out)/bin"
+  ];
+
+  preInstall = "mkdir -p $out/bin";
+
+  postFixup = ''
+    wrapProgram $out/bin/FET.pl --prefix PERL5LIB : $PERL5LIB
+    wrapProgram $out/bin/plot_2d.pl --prefix PERL5LIB : $PERL5LIB
+    wrapProgram $out/bin/clstr_list_sort.pl --prefix PERL5LIB : $PERL5LIB
+  '';
+  meta = with lib; {
+    description = "Clustering and comparing protein or nucleotide sequences";
+    homepage = "http://weizhongli-lab.org/cd-hit/";
+    license = licenses.gpl2;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/clustal-omega/default.nix
+++ b/pkgs/applications/science/biology/clustal-omega/default.nix
@ -0,0 +1,33 @@
+{ lib, stdenv, fetchurl, argtable }:
+
+stdenv.mkDerivation rec {
+  version = "1.2.4";
+  pname = "clustal-omega";
+
+  src = fetchurl {
+    url = "http://www.clustal.org/omega/${pname}-${version}.tar.gz";
+    sha256 = "1vm30mzncwdv881vrcwg11vzvrsmwy4wg80j5i0lcfk6dlld50w6";
+  };
+
+  buildInputs = [ argtable ];
+
+  preConfigure = ''
+    for f in configure \
+             src/clustal-omega-config.h \
+             src/clustal-omega-config.h \
+             src/config.h.in \
+             src/mymain.c
+    do
+      sed -i -re 's/argtable2/argtable3/g' $f
+    done
+  '';
+
+  meta = with lib; {
+    description = "General purpose multiple sequence alignment program for protein and DNA/RNA";
+    homepage = "http://www.clustal.org/omega/";
+    license = licenses.gpl2;
+    maintainers = [ maintainers.bzizou ];
+    mainProgram = "clustalo";
+    platforms = platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/cmtk/default.nix
+++ b/pkgs/applications/science/biology/cmtk/default.nix
@ -0,0 +1,31 @@
+{ lib, stdenv, fetchurl, cmake }:
+
+stdenv.mkDerivation rec {
+  pname = "cmtk";
+  version = "3.3.1";
+
+  src = fetchurl {
+    name = "cmtk-source.tar.gz";
+    url = "https://www.nitrc.org/frs/download.php/8198/CMTK-${version}-Source.tar.gz//?i_agree=1&download_now=1";
+    sha256 = "1nmsga9m7vcc4y4a6zl53ra3mwlgjwdgsq1j291awkn7zr1az6qs";
+  };
+
+  nativeBuildInputs = [ cmake ];
+
+  NIX_CFLAGS_COMPILE = [
+    "-std=c++11"
+    (lib.optional stdenv.cc.isClang "-Wno-error=c++11-narrowing")
+  ];
+
+  meta = with lib; {
+    broken = stdenv.isDarwin;
+    description = "Computational Morphometry Toolkit ";
+    longDescription = ''A software toolkit for computational morphometry of
+      biomedical images, CMTK comprises a set of command line tools and a
+      back-end general-purpose library for processing and I/O'';
+    maintainers = with maintainers; [ tbenst ];
+    platforms = platforms.all;
+    license = licenses.gpl3;
+    homepage = "https://www.nitrc.org/projects/cmtk/";
+  };
+}
--- a/pkgs/applications/science/biology/conglomerate/default.nix
+++ b/pkgs/applications/science/biology/conglomerate/default.nix
@ -0,0 +1,37 @@
+{ lib, stdenv, fetchFromGitHub, cmake, coreutils, perlPackages, bicpl, libminc, zlib, minc_tools,
+  makeWrapper }:
+
+stdenv.mkDerivation rec {
+  pname = "conglomerate";
+  version = "unstable-2017-09-10";
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "7343238bc6215942c7ecc885a224f24433a291b0";
+    sha256 = "1mlqgmy3jc13bv7d01rjwldxq0p4ayqic85xcl222hhifi3w2prr";
+  };
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ libminc zlib bicpl ];
+  propagatedBuildInputs = [ coreutils minc_tools ] ++ (with perlPackages; [ perl GetoptTabular MNI-Perllib ]);
+
+  cmakeFlags = [
+    "-DLIBMINC_DIR=${libminc}/lib/cmake"
+    "-DBICPL_DIR=${bicpl}/lib"
+  ];
+
+  postFixup = ''
+    for p in $out/bin/*; do
+      wrapProgram $p --prefix PERL5LIB : $PERL5LIB --set PATH "${lib.makeBinPath [ coreutils minc_tools ]}";
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/conglomerate";
+    description = "More command-line utilities for working with MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license   = licenses.free;
+  };
+}
--- a/pkgs/applications/science/biology/dcm2niix/default.nix
+++ b/pkgs/applications/science/biology/dcm2niix/default.nix
@ -0,0 +1,68 @@
+{ lib
+, stdenv
+, fetchFromGitHub
+, substituteAll
+, cmake
+, openjpeg
+, libyamlcpp
+, batchVersion ? false
+, withJpegLs ? true
+, withOpenJpeg ? true
+, withCloudflareZlib ? true
+}:
+
+let
+  cloudflareZlib = fetchFromGitHub {
+    owner = "ningfei";
+    repo = "zlib";
+    # HEAD revision of the gcc.amd64 branch on 2022-04-14. Reminder to update
+    # whenever bumping package version.
+    rev = "fda61188d1d4dcd21545c34c2a2f5cc9b0f5db4b";
+    sha256 = "sha256-qySFwY0VI2BQLO2XoCZeYshXEDnHh6SmJ3MvcBUROWU=";
+  };
+in
+stdenv.mkDerivation rec {
+  version = "1.0.20211006";
+  pname = "dcm2niix";
+
+  src = fetchFromGitHub {
+    owner = "rordenlab";
+    repo = "dcm2niix";
+    rev = "v${version}";
+    sha256 = "sha256-fQAVOzynMdSLDfhcYWcaXkFW/mnv4zySGLVJNE7ql/c=";
+  };
+
+  patches = lib.optionals withCloudflareZlib [
+    (substituteAll {
+      src = ./dont-fetch-external-libs.patch;
+      inherit cloudflareZlib;
+    })
+  ];
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = lib.optionals batchVersion [ libyamlcpp ]
+    ++ lib.optionals withOpenJpeg [ openjpeg openjpeg.dev ];
+
+  cmakeFlags = lib.optionals batchVersion [
+    "-DBATCH_VERSION=ON"
+    "-DYAML-CPP_DIR=${libyamlcpp}/lib/cmake/yaml-cpp"
+  ] ++ lib.optionals withJpegLs [
+    "-DUSE_JPEGLS=ON"
+  ] ++ lib.optionals withOpenJpeg [
+    "-DUSE_OPENJPEG=ON"
+    "-DOpenJPEG_DIR=${openjpeg}/lib/${openjpeg.pname}-${lib.versions.majorMinor openjpeg.version}"
+  ] ++ lib.optionals withCloudflareZlib [
+    "-DZLIB_IMPLEMENTATION=Cloudflare"
+  ];
+
+  meta = with lib; {
+    description = "DICOM to NIfTI converter";
+    longDescription = ''
+      dcm2niix is designed to convert neuroimaging data from the DICOM format to the NIfTI format.
+    '';
+    homepage = "https://www.nitrc.org/projects/dcm2nii";
+    license = licenses.bsd3;
+    maintainers = with maintainers; [ ashgillman rbreslow ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/dcm2niix/dont-fetch-external-libs.patch
+++ b/pkgs/applications/science/biology/dcm2niix/dont-fetch-external-libs.patch
@ -0,0 +1,36 @@
+diff --git a/SuperBuild/External-CLOUDFLARE-ZLIB.cmake b/SuperBuild/External-CLOUDFLARE-ZLIB.cmake
+index 9f064eb..fe74df5 100644
+--- a/SuperBuild/External-CLOUDFLARE-ZLIB.cmake
+++ b/SuperBuild/External-CLOUDFLARE-ZLIB.cmake
+@@ -1,8 +1,5 @@
+-set(CLOUDFLARE_BRANCH gcc.amd64) # Cloudflare zlib branch
+-
+ ExternalProject_Add(zlib
+-    GIT_REPOSITORY "${git_protocol}://github.com/ningfei/zlib.git"
+-    GIT_TAG "${CLOUDFLARE_BRANCH}"
+    URL file://@cloudflareZlib@
+     SOURCE_DIR cloudflare-zlib
+     BINARY_DIR cloudflare-zlib-build
+     CMAKE_ARGS
+diff --git a/SuperBuild/SuperBuild.cmake b/SuperBuild/SuperBuild.cmake
+index 2a0a956..81354a7 100644
+--- a/SuperBuild/SuperBuild.cmake
+++ b/SuperBuild/SuperBuild.cmake
+@@ -1,17 +1,3 @@
+-# Check if git exists
+-find_package(Git)
+-if(NOT GIT_FOUND)
+-    message(FATAL_ERROR "Cannot find Git. Git is required for Superbuild")
+-endif()
+-
+-# Use git protocol or not
+-option(USE_GIT_PROTOCOL "If behind a firewall turn this off to use http instead." ON)
+-if(USE_GIT_PROTOCOL)
+-    set(git_protocol "git")
+-else()
+-    set(git_protocol "https")
+-endif()
+-
+ # Basic CMake build settings
+ if(NOT CMAKE_BUILD_TYPE)
+     set(CMAKE_BUILD_TYPE "Release" CACHE STRING
--- a/pkgs/applications/science/biology/deeptools/default.nix
+++ b/pkgs/applications/science/biology/deeptools/default.nix
@ -0,0 +1,42 @@
+{ lib, python, fetchFromGitHub }:
+with python.pkgs;
+buildPythonApplication rec {
+  pname = "deepTools";
+  version = "3.5.1";
+
+  src = fetchFromGitHub {
+    owner = "deeptools";
+    repo = "deepTools";
+    rev = version;
+    sha256 = "07v8vb2x4b0mgw0mvcj91vj1fqbcwizwsniysl2cvmv93gad8gbp";
+  };
+
+  propagatedBuildInputs = [
+    numpy
+    numpydoc
+    scipy
+    py2bit
+    pybigwig
+    pysam
+    matplotlib
+    plotly
+    deeptoolsintervals
+  ];
+
+  checkInputs = [ nose ];
+
+  meta = with lib; {
+    homepage = "https://deeptools.readthedocs.io/en/develop";
+    description = "Tools for exploring deep DNA sequencing data";
+    longDescription = ''
+      deepTools contains useful modules to process the mapped reads data for multiple
+      quality checks, creating normalized coverage files in standard bedGraph and bigWig
+      file formats, that allow comparison between different files (for example, treatment and control).
+      Finally, using such normalized and standardized files, deepTools can create many
+      publication-ready visualizations to identify enrichments and for functional
+      annotations of the genome.
+    '';
+    license = licenses.gpl3;
+    maintainers = with maintainers; [ scalavision ];
+  };
+}
--- a/pkgs/applications/science/biology/delly/default.nix
+++ b/pkgs/applications/science/biology/delly/default.nix
@ -0,0 +1,40 @@
+{ lib, stdenv, fetchpatch, fetchFromGitHub, htslib, zlib, bzip2, xz, ncurses, boost }:
+
+stdenv.mkDerivation rec {
+  pname = "delly";
+  version = "0.9.1";
+
+  src = fetchFromGitHub {
+      owner = "dellytools";
+      repo = pname;
+      rev = "v${version}";
+      sha256 = "sha256-p1pryP+ktGt8OHFiASJQ3T+K94cNBG9fLxsJ2n/T+DA=";
+  };
+
+  buildInputs = [ zlib htslib bzip2 xz ncurses boost ];
+
+  EBROOTHTSLIB = htslib;
+
+  installPhase = ''
+    runHook preInstall
+
+    install -Dm555 src/delly $out/bin/delly
+
+    runHook postInstall
+  '';
+
+  meta = with lib; {
+    description = "Structural variant caller for mapped DNA sequenced data";
+    license = licenses.bsd3;
+    maintainers = with maintainers; [ scalavision ];
+    platforms = platforms.linux;
+    longDescription = ''
+      Delly is an integrated structural variant (SV) prediction method
+      that can discover, genotype and visualize deletions, tandem duplications,
+      inversions and translocations at single-nucleotide resolution in
+      short-read massively parallel sequencing data. It uses paired-ends,
+      split-reads and read-depth to sensitively and accurately delineate
+      genomic rearrangements throughout the genome.
+    '';
+  };
+}
--- a/pkgs/applications/science/biology/diamond/default.nix
+++ b/pkgs/applications/science/biology/diamond/default.nix
@ -0,0 +1,44 @@
+{ lib, stdenv, fetchFromGitHub, cmake, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "diamond";
+  version = "0.8.36";
+
+  src = fetchFromGitHub {
+    owner = "bbuchfink";
+    repo = "diamond";
+    rev = "v${version}";
+    sha256 = "sha256-7uqOQOzkYN0RNwKBGUZ/Ny5NVZMoGByOk+GUvjdBzck=";
+  };
+
+  patches = [
+    ./diamond-0.8.36-no-warning.patch
+  ];
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ zlib ];
+
+  meta = with lib; {
+    description = "Accelerated BLAST compatible local sequence aligner";
+    longDescription = ''
+      A sequence aligner for protein and translated DNA
+      searches and functions as a drop-in replacement for the NCBI BLAST
+      software tools. It is suitable for protein-protein search as well as
+      DNA-protein search on short reads and longer sequences including contigs
+      and assemblies, providing a speedup of BLAST ranging up to x20,000.
+
+      DIAMOND is developed by Benjamin Buchfink. Feel free to contact him for support (Email Twitter).
+
+      If you use DIAMOND in published research, please cite
+      B. Buchfink, Xie C., D. Huson,
+      "Fast and sensitive protein alignment using DIAMOND",
+      Nature Methods 12, 59-60 (2015).
+    '';
+    homepage = "https://github.com/bbuchfink/diamond";
+    license = {
+      fullName = "University of Tuebingen, Benjamin Buchfink";
+      url = "https://raw.githubusercontent.com/bbuchfink/diamond/master/src/COPYING";
+    };
+    maintainers = [ maintainers.metabar ];
+  };
+}
--- a/pkgs/applications/science/biology/diamond/diamond-0.8.36-no-warning.patch
+++ b/pkgs/applications/science/biology/diamond/diamond-0.8.36-no-warning.patch
@ -0,0 +1,20 @@
+diff -u -r diamond-0.8.36/src/dp/scalar_traceback.h diamond-0.8.36-patched/src/dp/scalar_traceback.h
+--- diamond-0.8.36/src/dp/scalar_traceback.h	2017-02-06 16:32:05.000000000 +0100
+++ diamond-0.8.36-patched/src/dp/scalar_traceback.h	2017-02-23 15:13:24.000000000 +0100
+@@ -19,6 +19,7 @@
+ #ifndef SCALAR_TRACEBACK_H_
+ #define SCALAR_TRACEBACK_H_
+ 
+#include <cmath>
+ #include <exception>
+ #include "../basic/score_matrix.h"
+ 
+@@ -31,7 +32,7 @@
+ template<>
+ inline bool almost_equal<float>(float x, float y)
+ {
+-	return abs(x - y) < 0.001f;
+	return std::abs(x - y) < 0.001f;
+ }
+ 
+ template<typename _score>
--- a/pkgs/applications/science/biology/ecopcr/default.nix
+++ b/pkgs/applications/science/biology/ecopcr/default.nix
@ -0,0 +1,38 @@
+{ lib, stdenv, fetchurl, gcc, zlib, python27 }:
+
+stdenv.mkDerivation rec {
+  pname = "ecopcr";
+  version = "0.8.0";
+
+  src = fetchurl {
+    url = "https://git.metabarcoding.org/obitools/ecopcr/uploads/6f37991b325c8c171df7e79e6ae8d080/ecopcr-${version}.tar.gz";
+    sha256 = "10c58hj25z78jh0g3zcbx4890yd2qrvaaanyx8mn9p49mmyf5pk6";
+  };
+
+  sourceRoot = "ecoPCR/src";
+
+  buildInputs = [ gcc python27 zlib ];
+
+  installPhase = ''
+    mkdir -p $out/bin
+    cp -v ecoPCR $out/bin
+    cp -v ecogrep $out/bin
+    cp -v ecofind $out/bin
+    cp -v ../tools/ecoPCRFormat.py $out/bin/ecoPCRFormat
+    chmod a+x $out/bin/ecoPCRFormat
+  '';
+
+  meta = with lib; {
+    description = "Electronic PCR software tool";
+    longDescription = ''
+      ecoPCR is an electronic PCR software developed by the LECA. It
+      helps you estimate Barcode primers quality. In conjunction with
+      OBITools, you can postprocess ecoPCR output to compute barcode
+      coverage and barcode specificity. New barcode primers can be
+      developed using the ecoPrimers software.
+    '';
+    homepage = "https://git.metabarcoding.org/obitools/ecopcr/wikis/home";
+    license = licenses.cecill20;
+    maintainers = [ maintainers.metabar ];
+  };
+}
--- a/pkgs/applications/science/biology/eggnog-mapper/default.nix
+++ b/pkgs/applications/science/biology/eggnog-mapper/default.nix
@ -0,0 +1,54 @@
+{ lib
+, autoPatchelfHook
+, fetchFromGitHub
+, python3Packages
+, wget
+, zlib
+}:
+
+python3Packages.buildPythonApplication rec {
+  pname = "eggnog-mapper";
+  version = "2.1.7";
+
+  src = fetchFromGitHub {
+    owner = "eggnogdb";
+    repo = pname;
+    rev = version;
+    hash = "sha256-auVD/r8m3TAB1KYMQ7Sae23eDg6LRx/daae0505cjwU=";
+  };
+
+  postPatch = ''
+    # Not a great solution...
+    substituteInPlace setup.cfg \
+      --replace "==" ">="
+  '';
+
+  nativeBuildInputs = [
+    autoPatchelfHook
+  ];
+
+  buildInputs = [
+    zlib
+  ];
+
+  propagatedBuildInputs = [
+    wget
+  ] ++ (with python3Packages; [
+    biopython
+    psutil
+    XlsxWriter
+  ]);
+
+  # Tests rely on some of the databases being available, which is not bundled
+  # with this package as (1) in total, they represent >100GB of data, and (2)
+  # the user can download only those that interest them.
+  doCheck = false;
+
+  meta = with lib; {
+    description = "Fast genome-wide functional annotation through orthology assignment";
+    license = licenses.gpl2;
+    homepage = "https://github.com/eggnogdb/eggnog-mapper/wiki";
+    maintainers = with maintainers; [ luispedro ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/emboss/default.nix
+++ b/pkgs/applications/science/biology/emboss/default.nix
@ -0,0 +1,30 @@
+{ lib, stdenv, fetchurl, readline, perl, libharu, libX11, libpng, libXt, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "emboss";
+  version = "6.6.0";
+
+  src = fetchurl {
+    url = "ftp://emboss.open-bio.org/pub/EMBOSS/EMBOSS-${version}.tar.gz";
+    sha256 = "7184a763d39ad96bb598bfd531628a34aa53e474db9e7cac4416c2a40ab10c6e";
+  };
+
+  buildInputs = [ readline perl libharu libpng libX11 libXt zlib ];
+
+  configureFlags = [ "--with-hpdf=${libharu}" "--with-pngdriver=${zlib}" ];
+
+  postConfigure = ''
+    sed -i 's@$(bindir)/embossupdate@true@' Makefile
+  '';
+
+  meta = {
+    description = "The European Molecular Biology Open Software Suite";
+    longDescription = ''EMBOSS is a free Open Source software analysis package
+    specially developed for the needs of the molecular biology (e.g. EMBnet)
+    user community, including libraries. The software automatically copes with
+    data in a variety of formats and even allows transparent retrieval of
+    sequence data from the web.'';
+    license = lib.licenses.gpl2;
+    homepage = "http://emboss.sourceforge.net/";
+  };
+}
--- a/pkgs/applications/science/biology/est-sfs/default.nix
+++ b/pkgs/applications/science/biology/est-sfs/default.nix
@ -0,0 +1,32 @@
+{ lib, stdenv, fetchurl, gsl }:
+
+stdenv.mkDerivation rec {
+  pname = "est-sfs";
+  version = "2.03";
+
+  src = fetchurl {
+    url = "mirror://sourceforge/est-usfs/${pname}-release-${version}.tar.gz";
+    sha256 = "1hvamrgagz0xi89w8qafyd9mjrdpyika8zm22drddnjkp4sdj65n";
+  };
+
+  buildInputs = [ gsl ];
+
+  makeFlags = [
+    "CC=${stdenv.cc.targetPrefix}cc"
+  ];
+
+  installPhase = ''
+    mkdir -p $out/bin
+    mkdir -p $out/share/doc/${pname}
+    cp est-sfs $out/bin
+    cp est-sfs-documentation.pdf $out/share/doc/${pname}
+  '';
+
+  meta = with lib; {
+    homepage = "https://sourceforge.net/projects/est-usfs";
+    description = "Estimate the unfolded site frequency spectrum and ancestral states";
+    license = licenses.gpl3;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/exonerate/default.nix
+++ b/pkgs/applications/science/biology/exonerate/default.nix
@ -0,0 +1,25 @@
+{ lib, stdenv, fetchurl, glib, pkg-config }:
+
+stdenv.mkDerivation rec {
+  version = "2.4.0";
+  pname = "exonerate";
+
+  src = fetchurl {
+    url = "http://ftp.ebi.ac.uk/pub/software/vertebrategenomics/exonerate/${pname}-${version}.tar.gz";
+    sha256 = "0hj0m9xygiqsdxvbg79wq579kbrx1mdrabi2bzqz2zn9qwfjcjgq";
+  };
+
+  doCheck = true;
+
+  buildInputs = [ glib ];
+
+  nativeBuildInputs = [ pkg-config ];
+
+  meta = with lib; {
+    description = "Generic tool for sequence alignment";
+    homepage = "https://www.ebi.ac.uk/about/vertebrate-genomics/software/exonerate";
+    license = licenses.gpl3;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix ;
+  };
+}
--- a/pkgs/applications/science/biology/fastp/default.nix
+++ b/pkgs/applications/science/biology/fastp/default.nix
@ -0,0 +1,33 @@
+{ lib
+, stdenv
+, fetchFromGitHub
+, zlib
+, libdeflate
+, isa-l
+}:
+
+stdenv.mkDerivation rec {
+  pname = "fastp";
+  version = "0.23.2";
+
+  src = fetchFromGitHub {
+    owner = "OpenGene";
+    repo = "fastp";
+    rev = "v${version}";
+    sha256 = "sha256-W1mXTfxD7/gHJhao6qqbNcyM3t2cfrUYiBYPJi/O1RI=";
+  };
+
+  buildInputs = [ zlib libdeflate isa-l ];
+
+  installPhase = ''
+    install -D fastp $out/bin/fastp
+  '';
+
+  meta = with lib; {
+    description = "Ultra-fast all-in-one FASTQ preprocessor";
+    license = licenses.mit;
+    homepage = "https://github.com/OpenGene/fastp";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/febio-studio/default.nix
+++ b/pkgs/applications/science/biology/febio-studio/default.nix
@ -0,0 +1,61 @@
+{ lib, stdenv, fetchFromGitHub, cmake, zlib, libglvnd, libGLU, wrapQtAppsHook
+, sshSupport ? true, openssl, libssh
+, tetgenSupport ? true, tetgen
+, ffmpegSupport ? true, ffmpeg
+, dicomSupport  ? false, dcmtk
+, withModelRepo ? true
+, withCadFeatures ? false
+}:
+
+stdenv.mkDerivation rec {
+  pname = "febio-studio";
+  version = "1.6.1";
+
+  src = fetchFromGitHub {
+    owner = "febiosoftware";
+    repo = "FEBioStudio";
+    rev = "v${version}";
+    sha256 = "0r6pg49i0q9idp7pjymj7mlxd63qjvmfvg0l7fmx87y1yd2hfw4h";
+  };
+
+  patches = [
+    ./febio-studio-cmake.patch # Fix Errors that appear with certain Cmake flags
+  ];
+
+  cmakeFlags = [
+    "-DQt_Ver=5"
+    "-DNOT_FIRST=On"
+    "-DOpenGL_GL_PREFERENCE=GLVND"
+  ]
+    ++ lib.optional sshSupport "-DUSE_SSH=On"
+    ++ lib.optional tetgenSupport "-DUSE_TETGEN=On"
+    ++ lib.optional ffmpegSupport "-DUSE_FFMPEG=On"
+    ++ lib.optional dicomSupport "-DUSE_DICOM=On"
+    ++ lib.optional withModelRepo "-DMODEL_REPO=On"
+    ++ lib.optional withCadFeatures "-DCAD_FEATURES=On"
+  ;
+
+
+  installPhase = ''
+    runHook preInstall
+    mkdir -p $out/
+    cp -R bin $out/
+    runHook postInstall
+  '';
+
+  nativeBuildInputs = [ cmake wrapQtAppsHook ];
+  buildInputs = [ zlib libglvnd libGLU openssl libssh ]
+    ++ lib.optional sshSupport openssl
+    ++ lib.optional tetgenSupport tetgen
+    ++ lib.optional ffmpegSupport ffmpeg
+    ++ lib.optional dicomSupport dcmtk
+  ;
+
+  meta = with lib; {
+    description = "FEBio Suite Solver";
+    license = with licenses; [ mit ];
+    homepage = "https://febio.org/";
+    platforms = platforms.unix;
+    maintainers = with maintainers; [ Scriptkiddi ];
+  };
+}
--- a/pkgs/applications/science/biology/febio-studio/febio-studio-cmake.patch
+++ b/pkgs/applications/science/biology/febio-studio/febio-studio-cmake.patch
@ -0,0 +1,38 @@
+diff --git a/FEBioStudio/RepositoryPanel.cpp b/FEBioStudio/RepositoryPanel.cpp
+index 382db303..314cdc68 100644
+--- a/FEBioStudio/RepositoryPanel.cpp
+++ b/FEBioStudio/RepositoryPanel.cpp
+@@ -1364,10 +1364,10 @@ void CRepositoryPanel::loadingPageProgress(qint64 bytesSent, qint64 bytesTotal)
+ 
+ #else
+ 
+-CRepositoryPanel::CRepositoryPanel(CMainWindow* pwnd, QWidget* parent){}
+CRepositoryPanel::CRepositoryPanel(CMainWindow* pwnd, QDockWidget* parent){}
+ CRepositoryPanel::~CRepositoryPanel(){}
+ void CRepositoryPanel::OpenLink(const QString& link) {}
+-// void CRepositoryPanel::Raise() {}
+void CRepositoryPanel::Raise() {}
+ void CRepositoryPanel::SetModelList(){}
+ void CRepositoryPanel::ShowMessage(QString message) {}
+ void CRepositoryPanel::ShowWelcomeMessage(QByteArray messages) {}
+@@ -1396,6 +1396,7 @@ void CRepositoryPanel::on_actionSearch_triggered() {}
+ void CRepositoryPanel::on_actionClearSearch_triggered() {}
+ void CRepositoryPanel::on_actionDeleteRemote_triggered() {}
+ void CRepositoryPanel::on_actionModify_triggered() {}
+void CRepositoryPanel::on_actionCopyPermalink_triggered() {}
+ void CRepositoryPanel::on_treeWidget_itemSelectionChanged() {}
+ void CRepositoryPanel::on_treeWidget_customContextMenuRequested(const QPoint &pos) {}
+ void CRepositoryPanel::DownloadItem(CustomTreeWidgetItem *item) {}
+diff --git a/FEBioStudio/WzdUpload.cpp b/FEBioStudio/WzdUpload.cpp
+index 5ce74346..20062e06 100644
+--- a/FEBioStudio/WzdUpload.cpp
+++ b/FEBioStudio/WzdUpload.cpp
+@@ -1183,7 +1183,7 @@ void CWzdUpload::on_saveJson_triggered()
+ 		getProjectJson(&projectInfo);
+ 
+ 		QFile file(filedlg.selectedFiles()[0]);
+-		file.open(QIODeviceBase::WriteOnly);
+		file.open(QIODevice::WriteOnly);
+ 		file.write(projectInfo);
+ 		file.close();
+ 	}
--- a/pkgs/applications/science/biology/flywheel-cli/default.nix
+++ b/pkgs/applications/science/biology/flywheel-cli/default.nix
@ -0,0 +1,49 @@
+{ lib
+, stdenv
+, fetchurl
+, unzip
+}:
+
+let
+  inherit (stdenv.targetPlatform) system;
+  throwSystem = throw "Unsupported system: ${system}";
+
+  os = {
+    x86_64-darwin = "darwin";
+    x86_64-linux = "linux";
+  }.${system} or throwSystem;
+
+  sha256 = {
+    x86_64-darwin = "sha256-OIyEu3Hsobui9s5+T9nC10SxMw0MhgmTA4SN9Ridyzo=";
+    x86_64-linux = "sha256-SxBjRd95hoh2zwX6IDnkZnTWVduQafPHvnWw8qTuM78=";
+  }.${system} or throwSystem;
+in
+stdenv.mkDerivation rec {
+  pname = "flywheel-cli";
+  version = "16.2.0";
+
+  src = fetchurl {
+    url = "https://storage.googleapis.com/flywheel-dist/cli/${version}/fw-${os}_amd64-${version}.zip";
+    inherit sha256;
+  };
+
+  nativeBuildInputs = [ unzip ];
+
+  unpackPhase = ''
+    unzip ${src}
+  '';
+
+  installPhase = ''
+    runHook preInstall
+    install -Dt $out/bin ./${os}_amd64/fw
+    runHook postInstall
+  '';
+
+  meta = with lib; {
+    description = "Library and command line interface for interacting with a Flywheel site";
+    homepage = "https://gitlab.com/flywheel-io/public/python-cli";
+    license = licenses.mit;
+    maintainers = with maintainers; [ rbreslow ];
+    platforms = [ "x86_64-darwin" "x86_64-linux" ];
+  };
+}
--- a/pkgs/applications/science/biology/freebayes/default.nix
+++ b/pkgs/applications/science/biology/freebayes/default.nix
@ -0,0 +1,35 @@
+{ lib, stdenv, fetchFromGitHub, zlib, bzip2, xz }:
+
+stdenv.mkDerivation rec {
+  pname = "freebayes";
+  version = "1.3.1";
+
+  src = fetchFromGitHub {
+    name = "freebayes-${version}-src";
+    owner  = "ekg";
+    repo   = "freebayes";
+    rev    = "v${version}";
+    sha256 = "035nriknjqq8gvil81vvsmvqwi35v80q8h1cw24vd1gdyn1x7bys";
+    fetchSubmodules = true;
+  };
+
+  buildInputs = [ zlib bzip2 xz ];
+
+  # Workaround build failure on -fno-common toolchains like upstream
+  # gcc-10. Otherwise build fails as:
+  #   ld: foomatic_rip-options.o:/build/foomatic-filters-4.0.17/options.c:49: multiple definition of `cupsfilter';
+  #     foomatic_rip-foomaticrip.o:/build/foomatic-filters-4.0.17/foomaticrip.c:158: first defined here
+  NIX_CFLAGS_COMPILE = "-fcommon";
+
+  installPhase = ''
+    install -vD bin/freebayes bin/bamleftalign scripts/* -t $out/bin
+  '';
+
+  meta = with lib; {
+    description = "Bayesian haplotype-based polymorphism discovery and genotyping";
+    license     = licenses.mit;
+    homepage    = "https://github.com/ekg/freebayes";
+    maintainers = with maintainers; [ jdagilliland ];
+    platforms = [ "x86_64-linux" ];
+  };
+}
--- a/pkgs/applications/science/biology/genmap/default.nix
+++ b/pkgs/applications/science/biology/genmap/default.nix
@ -0,0 +1,40 @@
+{ lib
+, stdenv
+, fetchFromGitHub
+, cmake
+, gtest
+, which
+}:
+
+stdenv.mkDerivation rec {
+  pname = "genmap";
+  version = "1.3.0";
+
+  src = fetchFromGitHub {
+    owner = "cpockrandt";
+    repo = "genmap";
+    rev = "genmap-v${version}";
+    fetchSubmodules = true;
+    sha256 = "sha256-7sIKBRMNzyCrZ/c2nXkknb6a5YsXe6DRE2IFhp6AviY=";
+  };
+
+  nativeBuildInputs = [ cmake ];
+
+  doCheck = true;
+  patches = [ ./gtest.patch ];
+  checkInputs = [ gtest which ];
+  preCheck = "make genmap_algo_test";
+
+  # disable benchmarks
+  preConfigure = ''
+    echo > benchmarks/CMakeLists.txt
+  '';
+
+  meta = {
+    description = "Ultra-fast computation of genome mappability";
+    license = lib.licenses.bsd3;
+    homepage = "https://github.com/cpockrandt/genmap";
+    maintainers = with lib.maintainers; [ jbedo ];
+    platforms = lib.platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/genmap/gtest.patch
+++ b/pkgs/applications/science/biology/genmap/gtest.patch
@ -0,0 +1,30 @@
+diff --git a/tests/CMakeLists.txt b/tests/CMakeLists.txt
+index 67ec8f9..ed0b2e0 100644
+--- a/tests/CMakeLists.txt
+++ b/tests/CMakeLists.txt
+@@ -2,23 +2,14 @@
+ #  GenMap tests
+ # ===========================================================================
+ 
+-include (ExternalProject)
+-ExternalProject_Add (googletest
+-                     PREFIX "${CMAKE_CURRENT_BINARY_DIR}/googletest"
+-                     GIT_REPOSITORY "https://github.com/google/googletest.git"
+-                     INSTALL_DIR "${CMAKE_CURRENT_BINARY_DIR}"
+-                     CMAKE_ARGS "-DCMAKE_INSTALL_PREFIX=${CMAKE_CURRENT_BINARY_DIR}"
+-                     GIT_TAG release-1.10.0
+-                     UPDATE_DISCONNECTED YES)
+ 
+ set (CMAKE_CXX_FLAGS "${CMAKE_CXX_FLAGS}") # TODO: --coverage
+ add_executable (genmap_algo_test tests.cpp)
+-add_dependencies (genmap_algo_test googletest)
+ 
+ include_directories (${CMAKE_CURRENT_BINARY_DIR}/include)
+ target_link_libraries (genmap_algo_test ${SEQAN_LIBRARIES})
+-target_link_libraries (genmap_algo_test ${CMAKE_CURRENT_BINARY_DIR}/lib/libgtest.a)
+-target_link_libraries (genmap_algo_test ${CMAKE_CURRENT_BINARY_DIR}/lib/libgtest_main.a)
+target_link_libraries (genmap_algo_test -lgtest)
+target_link_libraries (genmap_algo_test -lgtest_main)
+ target_link_libraries (genmap_algo_test pthread)
+ 
+ add_test(NAME algo_test COMMAND genmap_algo_test)
--- a/pkgs/applications/science/biology/hisat2/default.nix
+++ b/pkgs/applications/science/biology/hisat2/default.nix
@ -0,0 +1,46 @@
+{lib, stdenv, fetchFromGitHub, unzip, which, python3, perl}:
+
+stdenv.mkDerivation rec {
+  pname = "hisat2";
+  version = "2.2.1";
+
+  src = fetchFromGitHub {
+    owner = "DaehwanKimLab";
+    repo = "hisat2";
+    rev = "v${version}";
+    sha256 = "0lmzdhzjkvxw7n5w40pbv5fgzd4cz0f9pxczswn3d4cr0k10k754";
+  };
+
+  nativeBuildInputs = [ unzip which ];
+  buildInputs = [ python3 perl ];
+
+  installPhase = ''
+    mkdir -p $out/bin
+    cp hisat2 \
+       hisat2-inspect-l \
+       hisat2-build-s \
+       hisat2-align-l \
+       hisat2-inspect \
+       hisat2-align-s \
+       hisat2-inspect-s \
+       hisat2-build-l \
+       hisat2-build \
+       extract_exons.py \
+       extract_splice_sites.py \
+       hisat2_extract_exons.py \
+       hisat2_extract_snps_haplotypes_UCSC.py \
+       hisat2_extract_snps_haplotypes_VCF.py \
+       hisat2_extract_splice_sites.py \
+       hisat2_simulate_reads.py \
+       $out/bin
+  '';
+
+  meta = with lib; {
+    description = "Graph based aligner";
+    license = licenses.gpl3Plus;
+    homepage = "https://daehwankimlab.github.io/hisat2/";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = [ "x86_64-linux" "i686-linux" ];
+  };
+
+}
--- a/pkgs/applications/science/biology/hmmer/default.nix
+++ b/pkgs/applications/science/biology/hmmer/default.nix
@ -0,0 +1,26 @@
+{ lib, stdenv, fetchurl }:
+
+stdenv.mkDerivation rec {
+  version = "3.3.2";
+  pname = "hmmer";
+
+  src = fetchurl {
+    url = "http://eddylab.org/software/hmmer/${pname}-${version}.tar.gz";
+    sha256 = "0s9wf6n0qanbx8qs6igfl3vyjikwbrvh4d9d6mv54yp3xysykzlj";
+  };
+
+  meta = with lib; {
+    description = "Biosequence analysis using profile hidden Markov models";
+    longDescription = ''
+      HMMER is used for searching sequence databases for sequence homologs, and for making sequence alignments. It implements methods using probabilistic models called profile hidden Markov models (profile HMMs).
+      HMMER is often used together with a profile database, such as Pfam or many of the databases that participate in Interpro. But HMMER can also work with query sequences, not just profiles, just like BLAST. For example, you can search a protein query sequence against a database with phmmer, or do an iterative search with jackhmmer.
+      HMMER is designed to detect remote homologs as sensitively as possible, relying on the strength of its underlying probability models. In the past, this strength came at significant computational expense, but as of the new HMMER3 project, HMMER is now essentially as fast as BLAST.
+      HMMER can be downloaded and installed as a command line tool on your own hardware, and now it is also more widely accessible to the scientific community via new search servers at the European Bioinformatics Institute.
+    '';
+    homepage = "http://hmmer.org/";
+    license = licenses.gpl3;
+    maintainers = [ maintainers.iimog ];
+    # at least SSE is *required*
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/igv/default.nix
+++ b/pkgs/applications/science/biology/igv/default.nix
@ -0,0 +1,35 @@
+{ lib, stdenv, fetchzip, jdk11 }:
+
+stdenv.mkDerivation rec {
+  pname = "igv";
+  version = "2.8.13";
+  src = fetchzip {
+    url = "https://data.broadinstitute.org/igv/projects/downloads/2.8/IGV_${version}.zip";
+    sha256 = "0sab478jq96iw3fv0560hrrj8qbh40r8m4ncypdb7991j9haxl09";
+  };
+
+  installPhase = ''
+    mkdir -pv $out/{share,bin}
+    cp -Rv * $out/share/
+
+    sed -i "s#prefix=.*#prefix=$out/share#g" $out/share/igv.sh
+    sed -i 's#java#${jdk11}/bin/java#g' $out/share/igv.sh
+
+    sed -i "s#prefix=.*#prefix=$out/share#g" $out/share/igvtools
+    sed -i 's#java#${jdk11}/bin/java#g' $out/share/igvtools
+
+    ln -s $out/share/igv.sh $out/bin/igv
+    ln -s $out/share/igvtools $out/bin/igvtools
+
+    chmod +x $out/bin/igv
+    chmod +x $out/bin/igvtools
+  '';
+
+  meta = with lib; {
+    homepage = "https://www.broadinstitute.org/igv/";
+    description = "A visualization tool for interactive exploration of genomic datasets";
+    license = licenses.mit;
+    platforms = platforms.unix;
+    maintainers = [ maintainers.mimame ];
+  };
+}
--- a/pkgs/applications/science/biology/inormalize/default.nix
+++ b/pkgs/applications/science/biology/inormalize/default.nix
@ -0,0 +1,37 @@
+{ lib, stdenv, fetchFromGitHub, cmake, makeWrapper,
+  perlPackages,
+  libminc, EBTKS }:
+
+stdenv.mkDerivation rec {
+  pname = "inormalize";
+  name  = "${pname}-2014-10-21";
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "79cea9cdfe7b99abfd40afda89ab2253b596ad2f";
+    sha256 = "1ahqv5q0ljvji99a5q8azjkdf6bgp6nr8lwivkqwqs3jm0k5clq7";
+  };
+
+  patches = [ ./lgmask-interp.patch ./nu_correct_norm-interp.patch ];
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ libminc EBTKS ];
+  propagatedBuildInputs = with perlPackages; [ perl GetoptTabular MNI-Perllib ];
+
+  cmakeFlags = [ "-DLIBMINC_DIR=${libminc}/lib/cmake" "-DEBTKS_DIR=${EBTKS}/lib/" ];
+
+  postFixup = ''
+    for p in $out/bin/*; do
+      wrapProgram $p --prefix PERL5LIB : $PERL5LIB
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/${pname}";
+    description = "Program to normalize intensity of MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license   = licenses.free;
+  };
+}
--- a/pkgs/applications/science/biology/inormalize/lgmask-interp.patch
+++ b/pkgs/applications/science/biology/inormalize/lgmask-interp.patch
@ -0,0 +1,10 @@
+diff --git a/lgmask.in b/lgmask.in
+index 17dbe4d..2195d91 100644
+--- a/lgmask.in
+++ b/lgmask.in
+@@ -1,4 +1,4 @@
+-#! @PERL@
+#! /usr/bin/env perl
+ 
+ #---------------------------------------------------------------------------
+ #@COPYRIGHT :
--- a/pkgs/applications/science/biology/inormalize/nu_correct_norm-interp.patch
+++ b/pkgs/applications/science/biology/inormalize/nu_correct_norm-interp.patch
@ -0,0 +1,10 @@
+diff --git a/nu_correct_norm.in b/nu_correct_norm.in
+index 1dc84ac..1bc6235 100644
+--- a/nu_correct_norm.in
+++ b/nu_correct_norm.in
+@@ -1,4 +1,4 @@
+-#! @PERL@
+#! /usr/bin/perl
+  
+ #---------------------------------------------------------------------------
+ #@COPYRIGHT :
--- a/pkgs/applications/science/biology/itsx/default.nix
+++ b/pkgs/applications/science/biology/itsx/default.nix
@ -0,0 +1,34 @@
+{ lib, stdenv, fetchurl, hmmer, perl }:
+
+stdenv.mkDerivation rec {
+  version = "1.1.1";
+  pname = "itsx";
+
+  src = fetchurl {
+    url = "http://microbiology.se/sw/ITSx_${version}.tar.gz";
+    sha256 = "0lrmy2n3ax7f208k0k8l3yz0j5cpz05hv4hx1nnxzn0c51z1pc31";
+  };
+
+  buildInputs = [ hmmer perl ];
+
+  buildPhase = ''
+    sed -e "s,profileDB = .*,profileDB = \"$out/share/ITSx_db/HMMs\";," -i ITSx
+    sed "3 a \$ENV{\'PATH\'}='${hmmer}/bin:'.\"\$ENV{\'PATH\'}\";" -i ITSx
+    mkdir bin
+    mv ITSx bin
+  '';
+
+  installPhase = ''
+    mkdir -p $out/share/doc && cp -a bin $out/
+    cp *pdf $out/share/doc
+    cp -r ITSx_db $out/share
+  '';
+
+  meta = with lib; {
+    description = "Improved software detection and extraction of ITS1 and ITS2 from ribosomal ITS sequences of fungi and other eukaryotes for use in environmental sequencing";
+    homepage = "https://microbiology.se/software/itsx/";
+    license = licenses.gpl3;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/iv/default.nix
+++ b/pkgs/applications/science/biology/iv/default.nix
@ -0,0 +1,43 @@
+{ lib
+, stdenv
+, fetchurl
+, neuron-version
+, libX11
+, libXext
+, patchelf
+}:
+
+stdenv.mkDerivation rec {
+  pname = "iv";
+  version = "19";
+
+  src = fetchurl {
+    url = "https://www.neuron.yale.edu/ftp/neuron/versions/v${neuron-version}/iv-${version}.tar.gz";
+    sha256 = "07a3g8zzay4h0bls7fh89dd0phn7s34c2g15pij6dsnwpmjg06yx";
+  };
+
+  nativeBuildInputs = [ patchelf ];
+  buildInputs = [ libXext ];
+  propagatedBuildInputs = [ libX11 ];
+
+  hardeningDisable = [ "format" ];
+
+  postInstall = ''
+    for dir in $out/*; do # */
+      if [ -d $dir/lib ]; then
+        mv $dir/* $out # */
+        rmdir $dir
+        break
+      fi
+    done
+  '' + lib.optionalString stdenv.isLinux ''
+    patchelf --add-needed ${libX11}/lib/libX11.so $out/lib/libIVhines.so
+  '';
+
+  meta = with lib; {
+    description = "InterViews graphical library for Neuron";
+    license = licenses.bsd3;
+    homepage = "http://www.neuron.yale.edu/neuron";
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/kallisto/default.nix
+++ b/pkgs/applications/science/biology/kallisto/default.nix
@ -0,0 +1,30 @@
+{ lib, stdenv, fetchFromGitHub, autoconf, cmake, hdf5, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "kallisto";
+  version = "0.48.0";
+
+  src = fetchFromGitHub {
+    repo = "kallisto";
+    owner = "pachterlab";
+    rev = "v${version}";
+    sha256 = "sha256-r0cdR0jTRa1wu/LDKW6NdxI3XaKj6wcIVbIlct0fFvI=";
+  };
+
+  nativeBuildInputs = [ autoconf cmake ];
+
+  buildInputs = [ hdf5 zlib ];
+
+  cmakeFlags = [ "-DUSE_HDF5=ON" ];
+
+  # Parallel build fails in some cases: https://github.com/pachterlab/kallisto/issues/160
+  enableParallelBuilding = false;
+
+  meta = with lib; {
+    description = "Program for quantifying abundances of transcripts from RNA-Seq data";
+    homepage = "https://pachterlab.github.io/kallisto";
+    license = licenses.bsd2;
+    platforms = platforms.linux;
+    maintainers = with maintainers; [ arcadio ];
+  };
+}
--- a/pkgs/applications/science/biology/kent/default.nix
+++ b/pkgs/applications/science/biology/kent/default.nix
@ -0,0 +1,75 @@
+{ lib, stdenv
+, libpng
+, libuuid
+, zlib
+, bzip2
+, xz
+, openssl
+, curl
+, libmysqlclient
+, bash
+, fetchFromGitHub
+, which
+}:
+stdenv.mkDerivation rec {
+  pname = "kent";
+  version = "404";
+
+  src = fetchFromGitHub {
+    owner = "ucscGenomeBrowser";
+    repo = pname;
+    rev = "v${version}_base";
+    sha256 = "0l5lmqqc6sqkf4hyk3z4825ly0vdlj5xdfad6zd0708cb1v81nbx";
+  };
+
+  buildInputs = [ libpng libuuid zlib bzip2 xz openssl curl libmysqlclient ];
+
+  patchPhase = ''
+    substituteInPlace ./src/checkUmask.sh \
+      --replace "/bin/bash" "${bash}/bin/bash"
+
+    substituteInPlace ./src/hg/sqlEnvTest.sh \
+      --replace "which mysql_config" "${which}/bin/which ${libmysqlclient}/bin/mysql_config"
+  '';
+
+  buildPhase = ''
+    export MACHTYPE=$(uname -m)
+    export CFLAGS="-fPIC"
+    export MYSQLINC=$(mysql_config --include | sed -e 's/^-I//g')
+    export MYSQLLIBS=$(mysql_config --libs)
+    export DESTBINDIR=$NIX_BUILD_TOP/bin
+    export HOME=$NIX_BUILD_TOP
+
+    cd ./src
+    chmod +x ./checkUmask.sh
+    ./checkUmask.sh
+
+    mkdir -p $NIX_BUILD_TOP/lib
+    mkdir -p $NIX_BUILD_TOP/bin/x86_64
+
+    make libs
+    cd jkOwnLib
+    make
+
+    cp ../lib/x86_64/jkOwnLib.a $NIX_BUILD_TOP/lib
+    cp ../lib/x86_64/jkweb.a $NIX_BUILD_TOP/lib
+
+    cd ../utils
+    make
+  '';
+
+  installPhase = ''
+    mkdir -p $out/bin
+    mkdir -p $out/lib
+    cp $NIX_BUILD_TOP/lib/jkOwnLib.a $out/lib
+    cp $NIX_BUILD_TOP/lib/jkweb.a $out/lib
+    cp $NIX_BUILD_TOP/bin/x86_64/* $out/bin
+  '';
+
+  meta = with lib; {
+    description = "UCSC Genome Bioinformatics Group's suite of biological analysis tools, i.e. the kent utilities";
+    license = licenses.unfree;
+    maintainers = with maintainers; [ scalavision ];
+    platforms = platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/kssd/default.nix
+++ b/pkgs/applications/science/biology/kssd/default.nix
@ -0,0 +1,38 @@
+{ lib, stdenv, fetchFromGitHub, fetchpatch, zlib, automake, autoconf, libtool }:
+
+stdenv.mkDerivation rec {
+  pname = "kssd";
+  version = "1.1";
+
+  src = fetchFromGitHub {
+    owner = "yhg926";
+    repo = "public_kssd";
+    rev = "v${version}";
+    sha256 = "sha256-8jzYqo9LXF66pQ1EIusm+gba2VbTYpJz2K3NVlA3QxY=";
+  };
+
+  patches = [
+    # Pull upstream patch for -fno-common toolchain support:
+    #   https://github.com/yhg926/public_kssd/pull/9
+    (fetchpatch {
+      name = "fno-common.patch";
+      url = "https://github.com/yhg926/public_kssd/commit/cdd1e8aae256146f5913a3b4c723b638d53bdf27.patch";
+      sha256 = "sha256-HhaTRqPfKR+ouh0PwEH6u22pbuqbX2OypRzw8BXm0W4=";
+    })
+  ];
+
+  nativeBuildInputs = [ autoconf automake ];
+  buildInputs = [ zlib libtool ];
+
+  installPhase = ''
+      install -vD kssd $out/bin/kssd
+  '';
+
+  meta = with lib; {
+    description = "K-mer substring space decomposition";
+    license     = licenses.asl20;
+    homepage    = "https://github.com/yhg926/public_kssd";
+    maintainers = with maintainers; [ unode ];
+    platforms = [ "x86_64-linux" ];
+  };
+}
--- a/pkgs/applications/science/biology/last/default.nix
+++ b/pkgs/applications/science/biology/last/default.nix
@ -0,0 +1,32 @@
+{ lib, stdenv, fetchFromGitLab, unzip, zlib, python3, parallel }:
+
+stdenv.mkDerivation rec {
+  pname = "last";
+  version = "1268";
+
+  src = fetchFromGitLab {
+    owner = "mcfrith";
+    repo = "last";
+    rev = version;
+    sha256 = "sha256-9yzeLg3xporl32sZ1Ks8s63jXJNGUiI64XyQmhbQF4M=";
+  };
+
+  nativeBuildInputs = [ unzip ];
+  buildInputs = [ zlib python3 ];
+
+  makeFlags = [ "prefix=${placeholder "out"}" ];
+
+  postFixup = ''
+    for f in $out/bin/parallel-* ; do
+      sed -i 's|parallel |${parallel}/bin/parallel |' $f
+    done
+  '';
+
+  meta = with lib; {
+    description = "Genomic sequence aligner";
+    homepage = "https://gitlab.com/mcfrith/last";
+    license = licenses.gpl3Plus;
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/macse/default.nix
+++ b/pkgs/applications/science/biology/macse/default.nix
@ -0,0 +1,33 @@
+{ lib, stdenv, fetchurl, jre, makeWrapper }:
+
+stdenv.mkDerivation rec {
+  pname = "macse";
+  version = "2.03";
+
+  src = fetchurl {
+    url = "https://bioweb.supagro.inra.fr/${pname}/releases/${pname}_v${version}.jar";
+    sha256 = "0jnjyz4f255glg37rawzdv4m6nfs7wfwc5dny7afvx4dz2sv4ssh";
+  };
+
+  nativeBuildInputs = [ makeWrapper ];
+
+  dontUnpack = true;
+  dontBuild = true;
+
+  installPhase = ''
+    runHook preInstall
+    mkdir -p $out/share/java
+    cp -s $src $out/share/java/macse.jar
+    makeWrapper ${jre}/bin/java $out/bin/macse --add-flags "-jar $out/share/java/macse.jar"
+    runHook postInstall
+  '';
+
+  meta = with lib; {
+    description = "Multiple alignment of coding sequences";
+    homepage = "https://bioweb.supagro.inra.fr/macse/";
+    sourceProvenance = with sourceTypes; [ binaryBytecode ];
+    license = licenses.gpl2;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/manta/default.nix
+++ b/pkgs/applications/science/biology/manta/default.nix
@ -0,0 +1,35 @@
+{ lib, stdenv, fetchFromGitHub, cmake, zlib, python2 }:
+
+stdenv.mkDerivation rec {
+  pname = "manta";
+  version = "1.6.0";
+
+  src = fetchFromGitHub {
+    owner = "Illumina";
+    repo = "manta";
+    rev = "v${version}";
+    sha256 = "1711xkcw8rpw9xv3bbm7v1aryjz4r341rkq5255192dg38sgq7w2";
+  };
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ zlib python2 ];
+  postFixup = ''
+    sed -i 's|/usr/bin/env python2|${python2.interpreter}|' $out/lib/python/makeRunScript.py
+    sed -i 's|/usr/bin/env python|${python2.interpreter}|' $out/lib/python/pyflow/pyflow.py
+    sed -i 's|/bin/bash|${stdenv.shell}|' $out/lib/python/pyflow/pyflowTaskWrapper.py
+  '';
+  doInstallCheck = true;
+  installCheckPhase = ''
+    rm $out/lib/python/**/*.pyc
+    PYTHONPATH=$out/lib/python:$PYTHONPATH python -c 'import makeRunScript'
+    PYTHONPATH=$out/lib/python/pyflow:$PYTHONPATH python -c 'import pyflowTaskWrapper; import pyflow'
+  '';
+
+  meta = with lib; {
+    description = "Structural variant caller";
+    license = licenses.gpl3;
+    homepage = "https://github.com/Illumina/manta";
+    maintainers = with maintainers; [ jbedo ];
+    platforms =  platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/megahit/default.nix
+++ b/pkgs/applications/science/biology/megahit/default.nix
@ -0,0 +1,27 @@
+{ lib, stdenv, fetchFromGitHub, cmake, zlib }:
+
+stdenv.mkDerivation rec {
+  pname    = "megahit";
+  version = "1.2.9";
+
+  src = fetchFromGitHub {
+    owner = "voutcn";
+    repo = "megahit";
+    rev = "v${version}";
+    sha256 = "1r5d9nkdmgjsbrpj43q9hy3s8jwsabaz3ji561v18hy47v58923c";
+  };
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ zlib ];
+
+  cmakeFlags = lib.optional stdenv.hostPlatform.isStatic [
+    "-DSTATIC_BUILD=ON"
+    ];
+  meta = with lib; {
+    description = "An ultra-fast single-node solution for large and complex metagenomics assembly via succinct de Bruijn graph";
+    license     = licenses.gpl3;
+    homepage    = "https://github.com/voutcn/megahit";
+    maintainers = with maintainers; [ luispedro ];
+    platforms = [ "x86_64-linux" ];
+  };
+}
--- a/pkgs/applications/science/biology/meme-suite/default.nix
+++ b/pkgs/applications/science/biology/meme-suite/default.nix
@ -0,0 +1,21 @@
+{ lib, stdenv, fetchurl, python3, perl, glibc, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "meme-suite";
+  version = "5.1.1";
+
+  src = fetchurl {
+    url = "https://meme-suite.org/meme-software/${version}/meme-${version}.tar.gz";
+    sha256 = "38d73d256d431ad4eb7da2c817ce56ff2b4e26c39387ff0d6ada088938b38eb5";
+  };
+
+  buildInputs = [ zlib ];
+  nativeBuildInputs = [ perl python3 ];
+
+  meta = with lib; {
+    description = "Motif-based sequence analysis tools";
+    license = licenses.unfree;
+    maintainers = with maintainers; [ gschwartz ];
+    platforms = platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/messer-slim/default.nix
+++ b/pkgs/applications/science/biology/messer-slim/default.nix
@ -0,0 +1,26 @@
+{ lib, stdenv, fetchFromGitHub, cmake, gcc, gcc-unwrapped }:
+
+stdenv.mkDerivation rec {
+  version = "3.7.1";
+  pname = "messer-slim";
+
+  src = fetchFromGitHub {
+    owner = "MesserLab";
+    repo = "SLiM";
+    rev = "v${version}";
+    sha256 = "sha256-3ox+9hzqI8s4gmEkQ3Xm1Ih639LBtcSJNNmJgbpWaoM=";
+  };
+
+  nativeBuildInputs = [ cmake gcc gcc-unwrapped ];
+
+  cmakeFlags = [ "-DCMAKE_AR=${gcc-unwrapped}/bin/gcc-ar"
+                 "-DCMAKE_RANLIB=${gcc-unwrapped}/bin/gcc-ranlib" ];
+
+  meta = {
+     description = "An evolutionary simulation framework";
+     homepage = "https://messerlab.org/slim/";
+     license = with lib.licenses; [ gpl3 ];
+     maintainers = with lib.maintainers; [ bzizou ];
+     platforms = lib.platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/migrate/default.nix
+++ b/pkgs/applications/science/biology/migrate/default.nix
@ -0,0 +1,25 @@
+{ stdenv, lib, gccStdenv, fetchurl, zlib, mpi }:
+
+gccStdenv.mkDerivation rec {
+  version = "3.7.2";
+  pname = "migrate";
+
+  src = fetchurl {
+    url = "https://peterbeerli.com/migrate-html5/download_version3/${pname}-${version}.src.tar.gz";
+    sha256 = "1p2364ffjc56i82snzvjpy6pkf6wvqwvlvlqxliscx2c303fxs8v";
+  };
+
+  buildInputs = [ zlib mpi ];
+  setSourceRoot = "sourceRoot=$(echo */src)";
+  buildFlags = [ "thread" "mpis" ];
+  preInstall = "mkdir -p $out/man/man1";
+
+  meta = with lib; {
+    broken = stdenv.isDarwin;
+    description = "Estimates population size, migration, population splitting parameters using genetic/genomic data";
+    homepage = "https://peterbeerli.com/migrate-html5/index.html";
+    license = licenses.mit;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix;
+  };
+}
--- a/pkgs/applications/science/biology/minc-tools/default.nix
+++ b/pkgs/applications/science/biology/minc-tools/default.nix
@ -0,0 +1,36 @@
+{ lib, stdenv, fetchFromGitHub, cmake, makeWrapper, flex, bison, perl, TextFormat,
+  libminc, libjpeg, nifticlib, zlib }:
+
+stdenv.mkDerivation rec {
+  pname   = "minc-tools";
+  version = "unstable-2020-07-25";
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "fb0a68a07d281e4e099c5d54df29925240de14c1";
+    sha256 = "0zcv2sdj3k6k0xjqdq8j5bxq8smm48dzai90vwsmz8znmbbm6kvw";
+  };
+
+  nativeBuildInputs = [ cmake flex bison makeWrapper ];
+  buildInputs = [ libminc libjpeg nifticlib zlib ];
+  propagatedBuildInputs = [ perl TextFormat ];
+
+  cmakeFlags = [ "-DLIBMINC_DIR=${libminc}/lib/cmake"
+                 "-DZNZ_INCLUDE_DIR=${nifticlib}/include/nifti"
+                 "-DNIFTI_INCLUDE_DIR=${nifticlib}/include/nifti" ];
+
+  postFixup = ''
+    for prog in minccomplete minchistory mincpik; do
+      wrapProgram $out/bin/$prog --prefix PERL5LIB : $PERL5LIB
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/minc-tools";
+    description = "Command-line utilities for working with MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license   = licenses.free;
+  };
+}
--- a/pkgs/applications/science/biology/minc-widgets/default.nix
+++ b/pkgs/applications/science/biology/minc-widgets/default.nix
@ -0,0 +1,34 @@
+{ lib, stdenv, fetchFromGitHub, cmake, makeWrapper,
+  perlPackages,
+  libminc, octave, coreutils, minc_tools }:
+
+stdenv.mkDerivation rec {
+  pname = "minc-widgets";
+  name  = "${pname}-2016-04-20";
+
+
+  src = fetchFromGitHub {
+    owner  = "BIC-MNI";
+    repo   = pname;
+    rev    = "f08b643894c81a1a2e0fbfe595a17a42ba8906db";
+    sha256 = "1b9g6lf37wpp211ikaji4rf74rl9xcmrlyqcw1zq3z12ji9y33bm";
+  };
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ libminc ];
+  propagatedBuildInputs = (with perlPackages; [ perl GetoptTabular MNI-Perllib ]) ++ [ octave coreutils minc_tools ];
+
+  postFixup = ''
+    for p in $out/bin/*; do
+      wrapProgram $p --prefix PERL5LIB : $PERL5LIB --set PATH "${lib.makeBinPath [ coreutils minc_tools ]}";
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/${pname}";
+    description = "Collection of Perl and shell scripts for processing MINC files";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license = licenses.free;
+  };
+}
--- a/pkgs/applications/science/biology/minia/default.nix
+++ b/pkgs/applications/science/biology/minia/default.nix
@ -0,0 +1,33 @@
+{ lib, stdenv, fetchFromGitHub, cmake, hdf5, boost }:
+
+stdenv.mkDerivation rec {
+  pname = "minia";
+  version = "3.2.1";
+
+  src = fetchFromGitHub {
+    owner = "GATB";
+    repo = "minia";
+    rev = "v${version}";
+    sha256 = "0bmfrywixaaql898l0ixsfkhxjf2hb08ssnqzlzacfizxdp46siq";
+    fetchSubmodules = true;
+  };
+
+  patches = [ ./no-bundle.patch ];
+
+  NIX_CFLAGS_COMPILE = [ "-Wformat" ];
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ hdf5 boost ];
+
+  prePatch = ''
+    rm -rf thirdparty/gatb-core/gatb-core/thirdparty/{hdf5,boost}
+  '';
+
+  meta = with lib; {
+    description = "Short read genome assembler";
+    homepage = "https://github.com/GATB/minia";
+    license = licenses.agpl3;
+    maintainers = with maintainers; [ jbedo ];
+    platforms = [ "x86_64-linux" ];
+  };
+}
--- a/pkgs/applications/science/biology/minia/no-bundle.patch
+++ b/pkgs/applications/science/biology/minia/no-bundle.patch
@ -0,0 +1,222 @@
+diff --git a/thirdparty/gatb-core/gatb-core/CMakeLists.txt b/thirdparty/gatb-core/gatb-core/CMakeLists.txt
+index f48a70b..0e11ece 100644
+--- a/thirdparty/gatb-core/gatb-core/CMakeLists.txt
+++ b/thirdparty/gatb-core/gatb-core/CMakeLists.txt
+@@ -257,7 +257,6 @@ ADD_SUBDIRECTORY(thirdparty)
+ #  DEPENDENCIES 
+ ################################################################################
+ # we must be sure that hdf5 is built and installed before building gatb-core
+-ADD_DEPENDENCIES (gatbcore-static hdf5 hdf5_postbuild)
+ 
+ ################################################################################
+ #  DOCUMENTATION GENERATION 
+@@ -288,7 +287,6 @@ IF (NOT DEFINED GATB_CORE_INSTALL_EXCLUDE)
+     INSTALL (FILES ${PROJECT_SOURCE_DIR}/doc/misc/README.txt  DESTINATION . OPTIONAL)
+     INSTALL (FILES ${PROJECT_SOURCE_DIR}/LICENCE              DESTINATION . OPTIONAL)
+     INSTALL (FILES ${PROJECT_SOURCE_DIR}/THIRDPARTIES.md      DESTINATION . OPTIONAL)
+-    INSTALL (DIRECTORY ${PROJECT_SOURCE_DIR}/thirdparty/boost DESTINATION ./include)
+ ENDIF()
+ 
+ ################################################################################
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/LargeInt.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/LargeInt.hpp
+index dfeee1c..d5553a2 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/LargeInt.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/LargeInt.hpp
+@@ -35,7 +35,7 @@
+ #include <stdint.h>
+ #include <algorithm>
+ #include <iostream>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ #include <gatb/system/api/Exception.hpp>
+ #include <gatb/system/api/config.hpp>
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt128.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt128.hpp
+index 60be5d5..25ae75e 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt128.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt128.hpp
+@@ -33,7 +33,7 @@
+ /********************************************************************************/
+ 
+ #include <iostream>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ #include <gatb/system/api/types.hpp>
+ #include <gatb/tools/misc/api/Abundance.hpp>
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt16.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt16.hpp
+index 6a71bb0..b9205df 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt16.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt16.hpp
+@@ -31,7 +31,7 @@
+ #include <iostream>
+ #include <gatb/system/api/types.hpp>
+ #include <gatb/tools/misc/api/Abundance.hpp>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb  {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt32.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt32.hpp
+index c22b892..62e6586 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt32.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt32.hpp
+@@ -31,7 +31,7 @@
+ #include <iostream>
+ #include <gatb/system/api/types.hpp>
+ #include <gatb/tools/misc/api/Abundance.hpp>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb  {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt64.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt64.hpp
+index c06aaab..e0befba 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt64.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt64.hpp
+@@ -31,7 +31,7 @@
+ #include <iostream>
+ #include <gatb/system/api/types.hpp>
+ #include <gatb/tools/misc/api/Abundance.hpp>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ extern const unsigned char revcomp_4NT[];
+ extern const unsigned char comp_NT    [];
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt8.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt8.hpp
+index 9659874..0c79ff6 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt8.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/math/NativeInt8.hpp
+@@ -31,7 +31,7 @@
+ #include <iostream>
+ #include <gatb/system/api/types.hpp>
+ #include <gatb/tools/misc/api/Abundance.hpp>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb  {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/Abundance.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/Abundance.hpp
+index 3cb84f8..cd5d382 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/Abundance.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/Abundance.hpp
+@@ -31,7 +31,7 @@
+ /********************************************************************************/
+ 
+ #include <sys/types.h>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb      {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/IHistogram.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/IHistogram.hpp
+index b8f6c79..a040832 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/IHistogram.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/misc/api/IHistogram.hpp
+@@ -28,7 +28,7 @@
+ 
+ #include <gatb/system/api/ISmartPointer.hpp>
+ #include <gatb/tools/storage/impl/Storage.hpp>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb      {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5.hpp
+index 2645abd..fad48c0 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5.hpp
+@@ -40,7 +40,7 @@
+ #include <string>
+ #include <vector>
+ #include <stdarg.h>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb      {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5Patch.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5Patch.hpp
+index a92b729..66d552f 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5Patch.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/CollectionHDF5Patch.hpp
+@@ -40,7 +40,7 @@
+ #include <string>
+ #include <vector>
+ #include <stdarg.h>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ 
+ /********************************************************************************/
+ namespace gatb      {
+diff --git a/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/StorageHDF5.hpp b/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/StorageHDF5.hpp
+index 29e0949..0565cc4 100644
+--- a/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/StorageHDF5.hpp
+++ b/thirdparty/gatb-core/gatb-core/src/gatb/tools/storage/impl/StorageHDF5.hpp
+@@ -33,7 +33,7 @@
+ #include <gatb/tools/storage/impl/CollectionHDF5.hpp>
+ #include <gatb/tools/storage/impl/CollectionHDF5Patch.hpp>
+ #include <gatb/system/impl/System.hpp>
+-#include <hdf5/hdf5.h>
+#include <hdf5.h>
+ #include <sstream>
+ 
+ /********************************************************************************/
+diff --git a/thirdparty/gatb-core/gatb-core/thirdparty/CMakeLists.txt b/thirdparty/gatb-core/gatb-core/thirdparty/CMakeLists.txt
+index 6e0b5c4..34aef28 100644
+--- a/thirdparty/gatb-core/gatb-core/thirdparty/CMakeLists.txt
+++ b/thirdparty/gatb-core/gatb-core/thirdparty/CMakeLists.txt
+@@ -1,54 +1,3 @@
+-################################################################################
+-#  HDF5 GENERATION 
+-################################################################################
+-
+-#SET (HDF5_ENABLE_THREADSAFE       ON)
+-#SET (H5_HAVE_THREADSAFE 1)
+-
+-##########  MOMENTARY DEACTIVATED => CRASH ON MACOS TO BE INVESTIGATED  ##########
+-SET (HDF5_BUILD_TOOLS             ON CACHE BOOL "Build HDF5 Tools")
+-#SET (CMAKE_EXE_LINKER_FLAGS       "-lpthread -lz")
+-
+-SET (HDF5_EXTERNALLY_CONFIGURED     ON)
+-
+-#SET (HDF5_INSTALL_BIN_DIR           ${PROJECT_BINARY_DIR}/bin/${CMAKE_BUILD_TYPE})
+-#SET (HDF5_INSTALL_LIB_DIR           ${PROJECT_BINARY_DIR}/lib/${CMAKE_BUILD_TYPE})
+-SET (HDF5_INSTALL_BIN_DIR           bin)
+-SET (HDF5_INSTALL_LIB_DIR           lib)
+-
+-SET (HDF5_INSTALL_INCLUDE_DIR       ${PROJECT_BINARY_DIR}/include/${CMAKE_BUILD_TYPE}/hdf5)
+-SET (HDF5_INSTALL_DATA_DIR          ${PROJECT_BINARY_DIR}/share/${CMAKE_BUILD_TYPE})
+-SET (HDF5_INSTALL_CMAKE_DIR         ${PROJECT_BINARY_DIR}/share/${CMAKE_BUILD_TYPE})
+-
+-IF (NOT DEFINED GATB_CORE_INSTALL_EXCLUDE)
+-    SET (HDF5_EXPORTED_TARGETS          "gatb-hdf5")
+-ENDIF()
+-
+-IF (NOT DEFINED GATB_CORE_EXCLUDE_HDF5_ZLIB)
+-	OPTION (HDF5_ENABLE_Z_LIB_SUPPORT "Enable Zlib Filters" ON)
+-ENDIF()
+-
+-# We don't want warnings from HDF5 compilation
+-set (COMPILE_DEFINITIONS  "${COMPILE_DEFINITIONS}  -w")
+-add_definitions (${COMPILE_DEFINITIONS})
+-
+-# add HDF5 generation
+-ADD_SUBDIRECTORY (hdf5)
+-
+-# We add a custom target for copying header files.
+-add_custom_target (hdf5_postbuild ALL)
+-
+-# We build the output directory
+-add_custom_command (TARGET hdf5_postbuild POST_BUILD  COMMAND ${CMAKE_COMMAND} -E make_directory ${HDF5_INSTALL_INCLUDE_DIR})
+-
+-# We define all the header files to be copied
+-file (GLOB headerfiles ${PROJECT_SOURCE_DIR}/thirdparty/hdf5/src/*.h ${PROJECT_BINARY_DIR}/thirdparty/hdf5/H5pubconf.h)
+-
+-# We copy each header file
+-foreach (header ${headerfiles})
+-  add_custom_command (TARGET hdf5_postbuild POST_BUILD  COMMAND ${CMAKE_COMMAND} -E copy_if_different ${header} ${HDF5_INSTALL_INCLUDE_DIR}  )
+-endforeach()
+-
+ # include other smaller libraries (json, Boophf)
+ 
+ add_custom_target (thirdparty_copy ALL)
--- a/pkgs/applications/science/biology/minimap2/default.nix
+++ b/pkgs/applications/science/biology/minimap2/default.nix
@ -0,0 +1,32 @@
+{ lib, stdenv, fetchFromGitHub, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "minimap2";
+  version = "2.24";
+
+  src = fetchFromGitHub {
+    repo = pname;
+    owner = "lh3";
+    rev = "v${version}";
+    sha256 = "sha256-sEp7/Y5ifV9LTqrkhlkfykTJYMMuc+VtF7PvmIpBxUw=";
+  };
+
+  buildInputs = [ zlib ];
+
+  makeFlags = lib.optionals stdenv.isAarch64 [ "arm_neon=1" "aarch64=1" ];
+
+  installPhase = ''
+    mkdir -p $out/bin
+    cp minimap2 $out/bin
+    mkdir -p $out/share/man/man1
+    cp minimap2.1 $out/share/man/man1
+  '';
+
+  meta = with lib; {
+    description = "A versatile pairwise aligner for genomic and spliced nucleotide sequences";
+    homepage = "https://lh3.github.io/minimap2";
+    license = licenses.mit;
+    platforms = platforms.all;
+    maintainers = [ maintainers.arcadio ];
+  };
+}
--- a/pkgs/applications/science/biology/mni_autoreg/default.nix
+++ b/pkgs/applications/science/biology/mni_autoreg/default.nix
@ -0,0 +1,45 @@
+{ lib, stdenv, fetchFromGitHub, fetchpatch, cmake, makeWrapper, perlPackages, libminc }:
+
+stdenv.mkDerivation rec {
+  pname = "mni_autoreg";
+  version = "unstable-2017-09-22";
+
+  src = fetchFromGitHub {
+    owner = "BIC-MNI";
+    repo = pname;
+    rev = "ab99e29987dc029737785baebf24896ec37a2d76";
+    sha256 = "0axl069nv57vmb2wvqq7s9v3bfxwspzmk37bxm4973ai1irgppjq";
+  };
+
+  patches = [
+    # Pull upstream workaround for -fno-common toolchains:
+    #  https://github.com/BIC-MNI/mni_autoreg/pull/28
+    (fetchpatch {
+      name = "fno-common.patch";
+      url = "https://github.com/BIC-MNI/mni_autoreg/commit/06adfacbd84369ea3bcc4376596ac1c0f2e49af9.patch";
+      sha256 = "004sdrbx9kcj1qqwjly6p03svakl0x2sbv83salyg63fv67jynx8";
+    })
+  ];
+
+  nativeBuildInputs = [ cmake makeWrapper ];
+  buildInputs = [ libminc ];
+  propagatedBuildInputs = with perlPackages; [ perl GetoptTabular MNI-Perllib ];
+
+  cmakeFlags = [ "-DLIBMINC_DIR=${libminc}/lib/cmake" ];
+  # testing broken: './minc_wrapper: Permission denied' from Testing/ellipse0.mnc
+
+  postFixup = ''
+    for prog in autocrop mritoself mritotal xfmtool; do
+      echo $out/bin/$prog
+      wrapProgram $out/bin/$prog --prefix PERL5LIB : $PERL5LIB;
+    done
+  '';
+
+  meta = with lib; {
+    homepage = "https://github.com/BIC-MNI/mni_autoreg";
+    description = "Tools for automated registration using the MINC image format";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license = licenses.free;
+  };
+}
--- a/pkgs/applications/science/biology/mosdepth/default.nix
+++ b/pkgs/applications/science/biology/mosdepth/default.nix
@ -0,0 +1,24 @@
+{lib, nimPackages, fetchFromGitHub, pcre}:
+
+nimPackages.buildNimPackage rec {
+  pname = "mosdepth";
+  version = "0.3.3";
+  nimBinOnly = true;
+
+  src = fetchFromGitHub {
+    owner = "brentp";
+    repo = "mosdepth";
+    rev = "v${version}";
+    sha256 = "sha256-de3h3SXnXlqjuLT1L66jj/1AoiTuFc3PVJYjm7s8Fj8=";
+  };
+
+  buildInputs = with nimPackages; [ docopt hts-nim pcre ];
+
+  meta = with lib; {
+    description = "fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing";
+    license = licenses.mit;
+    homepage = "https://github.com/brentp/mosdepth";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/mrbayes/default.nix
+++ b/pkgs/applications/science/biology/mrbayes/default.nix
@ -0,0 +1,30 @@
+{ lib, stdenv, fetchFromGitHub, readline }:
+
+stdenv.mkDerivation rec {
+  pname = "mrbayes";
+  version = "3.2.7a";
+
+  src = fetchFromGitHub {
+    owner = "NBISweden";
+    repo = "MrBayes";
+    rev = "v${version}";
+    sha256 = "sha256-pkkxZ6YHRn/I1SJpT9A+EK4S5hWGmFdcDBJS0zh5mLA=";
+  };
+
+  meta = with lib; {
+    description = "Bayesian Inference of Phylogeny";
+    longDescription = ''
+      Bayesian inference of phylogeny is based upon a
+      quantity called the posterior probability distribution of trees, which is
+      the probability of a tree conditioned on the observations. The conditioning
+      is accomplished using Bayes's theorem. The posterior probability
+      distribution of trees is impossible to calculate analytically; instead,
+      MrBayes uses a simulation technique called Markov chain Monte Carlo (or
+      MCMC) to approximate the posterior probabilities of trees.
+    '';
+    maintainers = with maintainers; [ ];
+    license = licenses.gpl2Plus;
+    homepage = "https://nbisweden.github.io/MrBayes/";
+    platforms = platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/mrtrix/default.nix
+++ b/pkgs/applications/science/biology/mrtrix/default.nix
@ -0,0 +1,96 @@
+{ stdenv, lib, fetchFromGitHub, python, makeWrapper
+, eigen, fftw, libtiff, libpng, zlib, ants, bc
+, qt5, libGL, libGLU, libX11, libXext
+, withGui ? true, less }:
+
+stdenv.mkDerivation rec {
+  pname = "mrtrix";
+  version = "unstable-2021-11-25";
+
+  src = fetchFromGitHub {
+    owner  = "MRtrix3";
+    repo   = "mrtrix3";
+    rev    = "994498557037c9e4f7ba67f255820ef84ea899d9";
+    sha256 = "sha256-8eFDS5z4ZxMzi9Khk90KAS4ndma/Syd6JDXM2Fpr0M8=";
+    fetchSubmodules = true;
+  };
+
+  nativeBuildInputs = [ eigen makeWrapper ] ++ lib.optional withGui qt5.wrapQtAppsHook;
+
+  buildInputs = [
+    ants
+    python
+    fftw
+    libtiff
+    libpng
+    zlib
+  ] ++ lib.optionals withGui [
+    libGL
+    libGLU
+    libX11
+    libXext
+    qt5.qtbase
+    qt5.qtsvg
+  ];
+
+  installCheckInputs = [ bc ];
+
+  postPatch = ''
+    patchShebangs ./build ./configure ./run_tests ./bin/*
+
+    # patching interpreters before fixup is needed for tests:
+    patchShebangs ./bin/*
+    patchShebangs testing/binaries/data/vectorstats/*py
+
+    substituteInPlace ./run_tests  \
+      --replace 'git submodule update --init $datadir >> $LOGFILE 2>&1' ""
+
+    substituteInPlace ./build  \
+      --replace '"less -RX "' '"${less}/bin/less -RX "'
+  '';
+
+  configurePhase = ''
+    export EIGEN_CFLAGS="-isystem ${eigen}/include/eigen3"
+    unset LD  # similar to https://github.com/MRtrix3/mrtrix3/issues/1519
+    ./configure ${lib.optionalString (!withGui) "-nogui"};
+  '';
+
+  buildPhase = ''
+    ./build
+    (cd testing && ../build)
+  '';
+
+  installCheckPhase = ''
+    ./run_tests units
+    ./run_tests binaries
+
+    # can also `./run_tests scripts`, but this fails due to lack of FSL package
+    # (and there's no convenient way to disable individual tests)
+  '';
+  doInstallCheck = true;
+
+  installPhase = ''
+    runHook preInstall
+    mkdir -p $out
+    cp -ar lib $out/lib
+    cp -ar bin $out/bin
+    runHook postInstall
+  '';
+
+  postInstall = ''
+    for prog in $out/bin/*; do
+      if [[ -x "$prog" ]]; then
+        wrapProgram $prog --prefix PATH : ${lib.makeBinPath [ ants ]}
+      fi
+    done
+  '';
+
+  meta = with lib; {
+    broken = (stdenv.isLinux && stdenv.isAarch64);
+    homepage = "https://github.com/MRtrix3/mrtrix3";
+    description = "Suite of tools for diffusion imaging";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.linux;
+    license   = licenses.mpl20;
+  };
+}
--- a/pkgs/applications/science/biology/muscle/default.nix
+++ b/pkgs/applications/science/biology/muscle/default.nix
@ -0,0 +1,36 @@
+{ lib, stdenv, fetchurl }:
+
+stdenv.mkDerivation rec {
+  _name   = "muscle";
+  name    = "${_name}-${version}";
+  version = "3.8.31";
+
+  src = fetchurl {
+    url = "https://www.drive5.com/muscle/downloads${version}/${_name}${version}_src.tar.gz";
+    sha256 = "1b89z0x7h098g99g00nqadgjnb2r5wpi9s11b7ddffqkh9m9dia3";
+  };
+
+  patches = [
+    ./muscle-3.8.31-no-static.patch
+  ];
+
+  preBuild = ''
+    cd ./src/
+    patchShebangs mk
+  '';
+
+  installPhase = ''
+    install -vD muscle $out/bin/muscle
+  '';
+
+  meta = with lib; {
+    broken = (stdenv.isLinux && stdenv.isAarch64);
+    description = "A multiple sequence alignment method with reduced time and space complexity";
+    license     = licenses.publicDomain;
+    homepage    = "https://www.drive5.com/muscle/";
+    maintainers = [ maintainers.unode ];
+    # NOTE: Supposed to be compatible with darwin/intel & PPC but currently fails.
+    # Anyone with access to these platforms is welcome to give it a try
+    platforms   = lib.platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/muscle/muscle-3.8.31-no-static.patch
+++ b/pkgs/applications/science/biology/muscle/muscle-3.8.31-no-static.patch
@ -0,0 +1,21 @@
+--- a/src/mk	2010-05-02 01:15:42.000000000 +0200
+++ b/src/mk	2018-01-27 17:07:23.539092748 +0100
+@@ -5,14 +5,14 @@
+ rm -f *.o muscle.make.stdout.txt muscle.make.stderr.txt
+ for CPPName in $CPPNames
+ do
+-  echo $CPPName >> /dev/tty
+  echo $CPPName
+   g++ $ENV_GCC_OPTS -c -O3 -msse2 -mfpmath=sse -D_FILE_OFFSET_BITS=64 -DNDEBUG=1 $CPPName.cpp -o $CPPName.o  >> muscle.make.stdout.txt 2>> muscle.make.stderr.txt
+ done
+ 
+ LINK_OPTS=
+-if [ `uname -s` == Linux ] ; then
+-    LINK_OPTS=-static
+-fi
+#if [ `uname -s` == Linux ] ; then
+#    LINK_OPTS=-static
+#fi
+ g++ $LINK_OPTS $ENV_LINK_OPTS -g -o muscle $ObjNames  >> muscle.make.stdout.txt 2>> muscle.make.stderr.txt
+ tail muscle.make.stderr.txt
+ 
--- a/pkgs/applications/science/biology/neuron/default.nix
+++ b/pkgs/applications/science/biology/neuron/default.nix
@ -0,0 +1,89 @@
+{ lib, stdenv
+, fetchurl
+, pkg-config
+, automake
+, autoconf
+, libtool
+, ncurses
+, readline
+, which
+, python ? null
+, useMpi ? false
+, mpi
+, iv
+}:
+
+stdenv.mkDerivation rec {
+  pname = "neuron${lib.optionalString useMpi "-mpi"}";
+  version = "7.5";
+
+  nativeBuildInputs = [ which pkg-config automake autoconf libtool ];
+  buildInputs = [ ncurses readline python iv ]
+    ++ lib.optional useMpi mpi;
+
+  src = fetchurl {
+    url = "https://www.neuron.yale.edu/ftp/neuron/versions/v${version}/nrn-${version}.tar.gz";
+    sha256 = "0f26v3qvzblcdjg7isq0m9j2q8q7x3vhmkfllv8lsr3gyj44lljf";
+  };
+
+  patches = (lib.optional (stdenv.isDarwin) [ ./neuron-carbon-disable.patch ]);
+
+  # With LLVM 3.8 and above, clang (really libc++) gets upset if you attempt to redefine these...
+  postPatch = lib.optionalString stdenv.cc.isClang ''
+    substituteInPlace src/gnu/neuron_gnu_builtin.h \
+      --replace 'double abs(double arg);' "" \
+      --replace 'float abs(float arg);' "" \
+      --replace 'short abs(short arg);' "" \
+      --replace 'long abs(long arg);' ""
+  '' + lib.optionalString stdenv.isDarwin ''
+    # we are darwin, but we don't have all the quirks the source wants to compensate for
+    substituteInPlace src/nrnpython/setup.py.in --replace 'readline="edit"' 'readline="readline"'
+    for f in src/nrnpython/*.[ch] ; do
+      substituteInPlace $f --replace "<Python/Python.h>" "<Python.h>"
+    done
+  '';
+
+  enableParallelBuilding = true;
+
+  ## neuron install by default everything under prefix/${host_arch}/*
+  ## override this to support nix standard file hierarchy
+  ## without issues: install everything under prefix/
+  preConfigure = ''
+    ./build.sh
+    export prefix="''${prefix} --exec-prefix=''${out}"
+  '';
+
+  configureFlags = with lib;
+                    [ "--with-readline=${readline}" "--with-iv=${iv}" ]
+                    ++  optionals (python != null)  [ "--with-nrnpython=${python.interpreter}" ]
+                    ++ (if useMpi then ["--with-mpi" "--with-paranrn"]
+                        else ["--without-mpi"]);
+
+
+  postInstall = lib.optionalString (python != null) ''
+    ## standardise python neuron install dir if any
+    if [[ -d $out/lib/python ]]; then
+        mkdir -p ''${out}/${python.sitePackages}
+        mv ''${out}/lib/python/*  ''${out}/${python.sitePackages}/
+    fi
+  '';
+
+  propagatedBuildInputs = [ readline ncurses which libtool ];
+
+  meta = with lib; {
+    broken = stdenv.isDarwin;
+    description = "Simulation environment for empirically-based simulations of neurons and networks of neurons";
+
+    longDescription = "NEURON is a simulation environment for developing and exercising models of
+                neurons and networks of neurons. It is particularly well-suited to problems where
+                cable properties of cells play an important role, possibly including extracellular
+                potential close to the membrane), and where cell membrane properties are complex,
+                involving many ion-specific channels, ion accumulation, and second messengers";
+
+    license     = licenses.bsd3;
+    homepage    = "http://www.neuron.yale.edu/neuron";
+    maintainers = [ maintainers.adev ];
+    # source claims it's only tested for x86 and powerpc
+    platforms   = platforms.x86_64 ++ platforms.i686;
+  };
+}
--- a/pkgs/applications/science/biology/neuron/neuron-carbon-disable.patch
+++ b/pkgs/applications/science/biology/neuron/neuron-carbon-disable.patch
@ -0,0 +1,21 @@
+--- nrn-7.4/src/mac/Makefile.am	2015-11-12 21:42:45.000000000 +0100
+++ nrn-7.4.new/src/mac/Makefile.am	2016-08-24 17:43:39.000000000 +0200
+@@ -15,18 +15,8 @@
+ host_cpu = @host_cpu@
+ 
+ if MAC_DARWIN
+-carbon = @enable_carbon@
+ bin_SCRIPTS = $(launch_scripts)
+ install: install-am
+-if UniversalMacBinary
+-	$(CC) -arch ppc -o aoutppc -Dcpu="\"$(host_cpu)\"" -I. $(srcdir)/launch.c $(srcdir)/mac2uxarg.c -framework Carbon
+-	$(CC) -arch i386 -o aouti386 -Dcpu="\"$(host_cpu)\"" -I. $(srcdir)/launch.c $(srcdir)/mac2uxarg.c -framework Carbon
+-	lipo aouti386 aoutppc -create -output a.out
+-else
+-	gcc -g -arch i386 -Dncpu="\"$(host_cpu)\"" -I. $(srcdir)/launch.c $(srcdir)/mac2uxarg.c -framework Carbon
+-
+-endif
+-	carbon=$(carbon) sh $(srcdir)/launch_inst.sh "$(host_cpu)" "$(DESTDIR)$(prefix)" "$(srcdir)"
+ 	for i in $(S) ; do \
+ 		sed "s/^CPU.*/CPU=\"$(host_cpu)\"/" < $(DESTDIR)$(bindir)/$$i > temp; \
+ 		mv temp $(DESTDIR)$(bindir)/$$i; \
--- a/pkgs/applications/science/biology/niftyreg/default.nix
+++ b/pkgs/applications/science/biology/niftyreg/default.nix
@ -0,0 +1,24 @@
+{ lib, stdenv, fetchurl, cmake, zlib }:
+
+stdenv.mkDerivation rec {
+  pname   = "niftyreg";
+  version = "1.3.9";
+
+  src = fetchurl {
+    url = "mirror://sourceforge/${pname}/nifty_reg-${version}/nifty_reg-${version}.tar.gz";
+    sha256 = "07v9v9s41lvw72wpb1jgh2nzanyc994779bd35p76vg8mzifmprl";
+  };
+
+  NIX_CFLAGS_COMPILE = [ "-Wno-error=narrowing" ];
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ zlib ];
+
+  meta = with lib; {
+    homepage = "http://cmictig.cs.ucl.ac.uk/wiki/index.php/NiftyReg";
+    description = "Medical image registration software";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = [ "x86_64-linux" ];
+    license   = licenses.bsd3;
+  };
+}
--- a/pkgs/applications/science/biology/niftyseg/default.nix
+++ b/pkgs/applications/science/biology/niftyseg/default.nix
@ -0,0 +1,25 @@
+{ lib, stdenv, fetchFromGitHub, cmake, eigen, zlib }:
+
+stdenv.mkDerivation rec {
+  pname   = "niftyseg";
+  version = "1.0";
+
+  src = fetchFromGitHub {
+    owner = "KCL-BMEIS";
+    repo = "NiftySeg";
+    rev = "v${version}";
+    sha256 = "sha256-FDthq1ild9XOw3E3O7Lpfn6hBF1Frhv1NxfEA8500n8=";
+  };
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ eigen zlib ];
+
+  meta = with lib; {
+    homepage = "http://cmictig.cs.ucl.ac.uk/research/software/software-nifty/niftyseg";
+    description = "Software for medical image segmentation, bias field correction, and cortical thickness calculation";
+    maintainers = with maintainers; [ bcdarwin ];
+    platforms = platforms.unix;
+    license   = licenses.bsd3;
+  };
+
+}
--- a/pkgs/applications/science/biology/obitools/obitools3.nix
+++ b/pkgs/applications/science/biology/obitools/obitools3.nix
@ -0,0 +1,35 @@
+{ stdenv, lib, fetchurl, python3Packages, cmake, python3 }:
+
+python3Packages.buildPythonApplication rec {
+  pname = "obitools3";
+  version = "3.0.1b11";
+
+  src = fetchurl {
+    url = "https://git.metabarcoding.org/obitools/${pname}/repository/v${version}/archive.tar.gz";
+    sha256 = "1x7a0nrr9agg1pfgq8i1j8r1p6c0jpyxsv196ylix1dd2iivmas1";
+  };
+
+  nativeBuildInputs = [ python3Packages.cython cmake ];
+
+  postPatch = lib.optionalString stdenv.isAarch64 ''
+      substituteInPlace setup.py \
+      --replace "'-msse2'," ""
+  '';
+
+  preBuild = ''
+    substituteInPlace src/CMakeLists.txt --replace \$'{PYTHONLIB}' "$out/lib/${python3.libPrefix}/site-packages";
+    export NIX_CFLAGS_COMPILE="-L $out/lib/${python3.libPrefix}/site-packages $NIX_CFLAGS_COMPILE"
+  '';
+
+  dontConfigure = true;
+
+  doCheck = true;
+
+  meta = with lib ; {
+    description = "Management of analyses and data in DNA metabarcoding";
+    homepage = "https://git.metabarcoding.org/obitools/obitools3";
+    license = licenses.cecill20;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/octopus/default.nix
+++ b/pkgs/applications/science/biology/octopus/default.nix
@ -0,0 +1,29 @@
+{lib, stdenv, fetchFromGitHub, cmake, boost, gmp, htslib, zlib, xz, pkg-config}:
+
+stdenv.mkDerivation rec {
+  pname = "octopus";
+  version = "0.7.4";
+
+  src = fetchFromGitHub {
+    owner = "luntergroup";
+    repo = "octopus";
+    rev = "v${version}";
+    sha256 = "sha256-FAogksVxUlzMlC0BqRu22Vchj6VX+8yNlHRLyb3g1sE=";
+  };
+
+  nativeBuildInputs = [ cmake pkg-config ];
+  buildInputs = [ boost gmp htslib zlib xz ];
+
+  postInstall = ''
+    mkdir $out/bin
+    mv $out/octopus $out/bin
+  '';
+
+  meta = with lib; {
+    description = "Bayesian haplotype-based mutation calling";
+    license = licenses.mit;
+    homepage = "https://github.com/luntergroup/octopus";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/paml/default.nix
+++ b/pkgs/applications/science/biology/paml/default.nix
@ -0,0 +1,39 @@
+{stdenv, fetchurl}:
+
+stdenv.mkDerivation rec {
+  version = "4.9j";
+  pname = "paml";
+  src = fetchurl {
+    url = "http://abacus.gene.ucl.ac.uk/software/paml${version}.tgz";
+    sha256 = "0qflf3i27x6jwks3c6q560m1q8r043ja96syah145113iz5wdalp";
+  };
+
+  # Workaround build failure on -fno-common toolchains like upstream
+  # gcc-10. Otherwise build fails as:
+  #   ld: /build/ccKomtcd.o:(.bss+0x4544): multiple definition of `SeqTypes';
+  #     /build/ccx7EsgU.o:(.bss+0x2a0dfdc): first defined here
+  NIX_CFLAGS_COMPILE = "-fcommon";
+
+  preBuild = ''
+    cd ./src/
+  '';
+  installPhase = ''
+    mkdir -pv $out/bin
+    cp -v codeml $out/bin
+    cp -v baseml $out/bin
+    cp -v basemlg $out/bin
+    cp -v chi2 $out/bin
+    cp -v codeml $out/bin
+    cp -v evolver $out/bin
+    cp -v mcmctree $out/bin
+    cp -v pamp $out/bin
+    cp -v yn00 $out/bin
+  '';
+
+  meta = {
+    description     = "Phylogenetic Analysis by Maximum Likelihood (PAML)";
+    longDescription = "PAML is a package of programs for phylogenetic analyses of DNA or protein sequences using maximum likelihood. It is maintained and distributed for academic use free of charge by Ziheng Yang. ANSI C source codes are distributed for UNIX/Linux/Mac OSX, and executables are provided for MS Windows. PAML is not good for tree making. It may be used to estimate parameters and test hypotheses to study the evolutionary process, when you have reconstructed trees using other programs such as PAUP*, PHYLIP, MOLPHY, PhyML, RaxML, etc.";
+    license     = "non-commercial";
+    homepage    = "http://abacus.gene.ucl.ac.uk/software/paml.html";
+  };
+}
--- a/pkgs/applications/science/biology/picard-tools/default.nix
+++ b/pkgs/applications/science/biology/picard-tools/default.nix
@ -0,0 +1,33 @@
+{lib, stdenv, fetchurl, jre, makeWrapper}:
+
+stdenv.mkDerivation rec {
+  pname = "picard-tools";
+  version = "2.26.11";
+
+  src = fetchurl {
+    url = "https://github.com/broadinstitute/picard/releases/download/${version}/picard.jar";
+    sha256 = "sha256-0swggo1a5gExpj3VgaWKT/TYd7rfSFBcqRrAURnTPjM=";
+  };
+
+  nativeBuildInputs = [ makeWrapper ];
+  buildInputs = [ jre ];
+
+  dontUnpack = true;
+
+  installPhase = ''
+    mkdir -p $out/libexec/picard
+    cp $src $out/libexec/picard/picard.jar
+    mkdir -p $out/bin
+    makeWrapper ${jre}/bin/java $out/bin/picard --add-flags "-jar $out/libexec/picard/picard.jar"
+  '';
+
+  meta = with lib; {
+    description = "Tools for high-throughput sequencing (HTS) data and formats such as SAM/BAM/CRAM and VCF";
+    license = licenses.mit;
+    homepage = "https://broadinstitute.github.io/picard/";
+    sourceProvenance = with sourceTypes; [ binaryBytecode ];
+    maintainers = with maintainers; [ jbedo ];
+    mainProgram = "picard";
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/platypus/default.nix
+++ b/pkgs/applications/science/biology/platypus/default.nix
@ -0,0 +1,39 @@
+{lib, stdenv, fetchFromGitHub, python27, htslib, zlib, makeWrapper}:
+
+let python = python27.withPackages (ps: with ps; [ cython ]);
+
+in stdenv.mkDerivation {
+  pname = "platypus-unstable";
+  version = "2018-07-22";
+
+  src = fetchFromGitHub {
+    owner = "andyrimmer";
+    repo = "Platypus";
+    rev = "3e72641c69800da0cd4906b090298e654d316ee1";
+    sha256 = "0nah6r54b8xm778gqyb8b7rsd76z8ji4g73sm6rvpw5s96iib1vw";
+  };
+
+  nativeBuildInputs = [ makeWrapper ];
+  buildInputs = [ htslib python zlib ];
+
+  buildPhase = ''
+    patchShebangs .
+    make
+  '';
+
+  installPhase = ''
+    mkdir -p $out/libexec/platypus
+    cp -r ./* $out/libexec/platypus
+
+    mkdir -p $out/bin
+    makeWrapper ${python}/bin/python $out/bin/platypus --add-flags "$out/libexec/platypus/bin/Platypus.py"
+  '';
+
+  meta = with lib; {
+    description = "The Platypus variant caller";
+    license = licenses.gpl3;
+    homepage = "https://github.com/andyrimmer/Platypus";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/plink-ng/default.nix
+++ b/pkgs/applications/science/biology/plink-ng/default.nix
@ -0,0 +1,40 @@
+{ lib, stdenv, fetchFromGitHub, zlib, blas, lapack, darwin}:
+
+stdenv.mkDerivation rec {
+  pname = "plink-ng";
+  version = "1.90b3";
+
+  src = fetchFromGitHub {
+    owner = "chrchang";
+    repo = "plink-ng";
+    rev = "v${version}";
+    sha256 = "1zhffjbwpd50dxywccbnv1rxy9njwz73l4awc5j7i28rgj3davcq";
+  };
+
+  buildInputs = [ zlib ] ++ (if stdenv.isDarwin then [ darwin.apple_sdk.frameworks.Accelerate ] else [ blas lapack ]) ;
+
+  preBuild = ''
+    sed -i 's|zlib-1.2.8/zlib.h|zlib.h|g' *.c *.h
+    ${if stdenv.cc.isClang then "sed -i 's|g++|clang++|g' Makefile.std" else ""}
+
+    makeFlagsArray+=(
+      ZLIB=-lz
+      BLASFLAGS="-lblas -lcblas -llapack"
+    );
+  '';
+
+  makefile = "Makefile.std";
+
+  installPhase = ''
+    mkdir -p $out/bin
+    cp plink $out/bin
+  '';
+
+  meta = {
+    broken = (stdenv.isLinux && stdenv.isAarch64);
+    description = "A comprehensive update to the PLINK association analysis toolset";
+    homepage = "https://www.cog-genomics.org/plink2";
+    license = lib.licenses.gpl3;
+    platforms = lib.platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/poretools/default.nix
+++ b/pkgs/applications/science/biology/poretools/default.nix
@ -0,0 +1,22 @@
+{ lib, python2Packages, fetchFromGitHub }:
+
+python2Packages.buildPythonPackage rec {
+  pname = "poretools";
+  version = "unstable-2016-07-10";
+
+  src = fetchFromGitHub {
+    repo = pname;
+    owner = "arq5x";
+    rev = "e426b1f09e86ac259a00c261c79df91510777407";
+    sha256 = "0bglj833wxpp3cq430p1d3xp085ls221js2y90w7ir2x5ay8l7am";
+  };
+
+  propagatedBuildInputs = [python2Packages.h5py python2Packages.matplotlib python2Packages.seaborn python2Packages.pandas];
+
+  meta = {
+    description = "a toolkit for working with nanopore sequencing data from Oxford Nanopore";
+    license = lib.licenses.mit;
+    homepage = "https://poretools.readthedocs.io/en/latest/";
+    maintainers = [lib.maintainers.rybern];
+  };
+}
--- a/pkgs/applications/science/biology/prodigal/default.nix
+++ b/pkgs/applications/science/biology/prodigal/default.nix
@ -0,0 +1,26 @@
+{ lib, stdenv, fetchFromGitHub }:
+
+stdenv.mkDerivation rec {
+  pname = "prodigal";
+  version = "2.6.3";
+
+  src = fetchFromGitHub {
+    repo = "Prodigal";
+    owner = "hyattpd";
+    rev = "v${version}";
+    sha256 = "1fs1hqk83qjbjhrvhw6ni75zakx5ki1ayy3v6wwkn3xvahc9hi5s";
+  };
+
+  makeFlags = [
+    "CC=${stdenv.cc.targetPrefix}cc"
+    "INSTALLDIR=$(out)/bin"
+  ];
+
+  meta = with lib; {
+    description = "Fast, reliable protein-coding gene prediction for prokaryotic genomes";
+    homepage = "https://github.com/hyattpd/Prodigal";
+    license = licenses.gpl3;
+    platforms = platforms.all;
+    maintainers = with maintainers; [ luispedro ];
+  };
+}
--- a/pkgs/applications/science/biology/quast/default.nix
+++ b/pkgs/applications/science/biology/quast/default.nix
@ -0,0 +1,56 @@
+{ lib, stdenv, fetchurl, python3Packages, zlib, bash }:
+
+let
+  pythonPackages = python3Packages;
+  inherit (pythonPackages) python;
+in
+
+pythonPackages.buildPythonApplication rec {
+  pname = "quast";
+  version = "5.0.2";
+
+  src = fetchurl {
+    url = "https://github.com/ablab/quast/releases/download/${pname}_${version}/${pname}-${version}.tar.gz";
+    sha256 = "13ml8qywbb4cc7wf2x7z5mz1rjqg51ab8wkizwcg4f6c40zgif6d";
+  };
+
+  pythonPath = with pythonPackages; [ simplejson joblib setuptools matplotlib ];
+
+  buildInputs = [ zlib ] ++ pythonPath;
+
+  dontConfigure = true;
+
+  dontBuild = true;
+
+  installPhase = ''
+    substituteInPlace quast_libs/bedtools/Makefile \
+      --replace "/bin/bash" "${bash}/bin/bash"
+    mkdir -p "$out/${python.sitePackages}"
+    export PYTHONPATH="$out/${python.sitePackages}:$PYTHONPATH"
+    ${python.interpreter} setup.py install \
+      --install-lib=$out/${python.sitePackages} \
+      --prefix="$out"
+  '';
+
+   postFixup = ''
+   for file in $(find $out -type f -type f -perm /0111); do
+       old_rpath=$(patchelf --print-rpath $file) && \
+       patchelf --set-rpath $old_rpath:${stdenv.cc.cc.lib}/lib $file || true
+   done
+   # Link to the master program
+   ln -s $out/bin/quast.py $out/bin/quast
+  '';
+
+  dontPatchELF = true;
+
+  # Tests need to download data files, so manual run after packaging is needed
+  doCheck = false;
+
+  meta = with lib ; {
+    description = "Evaluates genome assemblies by computing various metrics";
+    homepage = "https://github.com/ablab/quast";
+    license = licenses.gpl2;
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.all;
+  };
+}
--- a/pkgs/applications/science/biology/raxml/default.nix
+++ b/pkgs/applications/science/biology/raxml/default.nix
@ -0,0 +1,40 @@
+{ lib, stdenv
+, fetchFromGitHub
+, useMpi ? false
+, mpi
+}:
+
+stdenv.mkDerivation rec {
+  pname = "RAxML${lib.optionalString useMpi "-mpi"}";
+  version = "8.2.12";
+
+  src = fetchFromGitHub {
+    owner = "stamatak";
+    repo = "standard-RAxML";
+    rev = "v${version}";
+    sha256 = "1jqjzhch0rips0vp04prvb8vmc20c5pdmsqn8knadcf91yy859fh";
+  };
+
+  buildInputs = lib.optionals useMpi [ mpi ];
+
+  # TODO darwin, AVX and AVX2 makefile targets
+  buildPhase = if useMpi then ''
+      make -f Makefile.MPI.gcc
+    '' else ''
+      make -f Makefile.SSE3.PTHREADS.gcc
+    '';
+
+  installPhase = if useMpi then ''
+    mkdir -p $out/bin && cp raxmlHPC-MPI $out/bin
+  '' else ''
+    mkdir -p $out/bin && cp raxmlHPC-PTHREADS-SSE3 $out/bin
+  '';
+
+  meta = with lib; {
+    description = "A tool for Phylogenetic Analysis and Post-Analysis of Large Phylogenies";
+    license = licenses.gpl3;
+    homepage = "https://sco.h-its.org/exelixis/web/software/raxml/";
+    maintainers = [ maintainers.unode ];
+    platforms = [ "i686-linux" "x86_64-linux" ];
+  };
+}
--- a/pkgs/applications/science/biology/repseek/default.nix
+++ b/pkgs/applications/science/biology/repseek/default.nix
@ -0,0 +1,27 @@
+{ lib, stdenv, fetchurl }:
+
+stdenv.mkDerivation rec {
+  pname = "repseek";
+  version = "9Sep2014";
+  src = fetchurl {
+    url = "https://bioinfo.mnhn.fr/abi/public/RepSeek/RepSeek.${version}.tgz";
+    sha256 = "1jiknji3ivrv7zmrfbf2mccfpdwhin3lfxfsciaqwf69b3sda8nf";
+  };
+
+  preConfigure = ''
+    mkdir -p $out/bin
+    substituteInPlace Makefile \
+      --replace "INSTALLDIR = \$\$HOME/bin" "INSTALLDIR = $out/bin/" \
+      --replace "CC= gcc" "CC = $CC"
+  '' + lib.optionalString stdenv.isLinux ''
+    substituteInPlace Makefile --replace "MACHINE = MACOSX" "MACHINE = LINUX"
+  '';
+
+  meta = {
+    description = "Tool to retrieve approximate repeats from large DNA sequences";
+    homepage = "https://bioinfo.mnhn.fr/abi/public/RepSeek";
+    maintainers = [ lib.maintainers.bzizou ];
+    license = lib.licenses.lgpl21;
+  };
+
+}
--- a/pkgs/applications/science/biology/sambamba/default.nix
+++ b/pkgs/applications/science/biology/sambamba/default.nix
@ -0,0 +1,39 @@
+{ lib
+, stdenv
+, fetchFromGitHub
+, python3
+, which
+, ldc
+, zlib
+, lz4
+}:
+
+stdenv.mkDerivation rec {
+  pname = "sambamba";
+  version = "0.8.2";
+
+  src = fetchFromGitHub {
+    owner = "biod";
+    repo = "sambamba";
+    rev = "v${version}";
+    sha256 = "sha256-FEa9QjQoGNUOAtMNMZcqpTKMKVtXoBuOomTy0mpos/0=";
+    fetchSubmodules = true;
+  };
+
+  nativeBuildInputs = [ which python3 ldc ];
+  buildInputs = [ zlib lz4 ];
+
+  # Upstream's install target is broken; copy manually
+  installPhase = ''
+    mkdir -p $out/bin
+    cp bin/sambamba-${version} $out/bin/sambamba
+  '';
+
+  meta = with lib; {
+    description = "SAM/BAM processing tool";
+    homepage = "https://lomereiter.github.io/sambamba/";
+    maintainers = with maintainers; [ jbedo ];
+    license = with licenses; gpl2;
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/samblaster/default.nix
+++ b/pkgs/applications/science/biology/samblaster/default.nix
@ -0,0 +1,28 @@
+{ lib, stdenv, fetchFromGitHub }:
+
+stdenv.mkDerivation rec {
+  pname = "samblaster";
+  version = "0.1.26";
+
+  src = fetchFromGitHub {
+    owner = "GregoryFaust";
+    repo = "samblaster";
+    rev = "v.${version}";
+    sha256 = "0g24fq5hplnfgqkh3xqpg3lgx3wmxwnh9c7m6yw7pbi40lmgl1jv";
+  };
+
+  makeFlags = [ "CPP=${stdenv.cc.targetPrefix}c++" ];
+
+  installPhase = ''
+    mkdir -p $out/bin
+    cp samblaster $out/bin
+  '';
+
+  meta = with lib; {
+    description = "Tool for marking duplicates and extracting discordant/split reads from SAM/BAM files";
+    maintainers = with maintainers; [ jbedo ];
+    license = licenses.mit;
+    homepage = "https://github.com/GregoryFaust/samblaster";
+    platforms = platforms.x86_64;
+  };
+}
--- a/pkgs/applications/science/biology/samtools/default.nix
+++ b/pkgs/applications/science/biology/samtools/default.nix
@ -0,0 +1,50 @@
+{ lib, stdenv, fetchurl, fetchpatch, zlib, htslib, perl, ncurses ? null }:
+
+stdenv.mkDerivation rec {
+  pname = "samtools";
+  version = "1.13";
+
+  src = fetchurl {
+    url = "https://github.com/samtools/samtools/releases/download/${version}/${pname}-${version}.tar.bz2";
+    sha256 = "sha256-YWyi4FHMgAmh6cAc/Yx8r4twkW3f9m87dpFAeUZfjGA=";
+  };
+
+  patches = [
+    # Pull upstream patch for ncurses-6.3 support
+    (fetchpatch {
+      name = "ncurses-6.3.patch";
+      url = "https://github.com/samtools/samtools/commit/396ef20eb0854d6b223c3223b60bb7efe42301f7.patch";
+      sha256 = "sha256-p0l9ymXK9nqL2w8EytbW+qeaI7dD86IQgIVxacBj838=";
+    })
+  ];
+
+  nativeBuildInputs = [ perl ];
+
+  buildInputs = [ zlib ncurses htslib ];
+
+  preConfigure = lib.optional stdenv.hostPlatform.isStatic ''
+    export LIBS="-lz -lbz2 -llzma"
+  '';
+  makeFlags = lib.optional stdenv.hostPlatform.isStatic "AR=${stdenv.cc.targetPrefix}ar";
+
+  configureFlags = [ "--with-htslib=${htslib}" ]
+    ++ lib.optional (ncurses == null) "--without-curses"
+    ++ lib.optional stdenv.hostPlatform.isStatic ["--without-curses" ]
+    ;
+
+  preCheck = ''
+    patchShebangs test/
+  '';
+
+  enableParallelBuilding = true;
+
+  doCheck = true;
+
+  meta = with lib; {
+    description = "Tools for manipulating SAM/BAM/CRAM format";
+    license = licenses.mit;
+    homepage = "http://www.htslib.org/";
+    platforms = platforms.unix;
+    maintainers = with maintainers; [ mimame unode ];
+  };
+}
--- a/pkgs/applications/science/biology/samtools/samtools-0.1.19-no-curses.patch
+++ b/pkgs/applications/science/biology/samtools/samtools-0.1.19-no-curses.patch
@ -0,0 +1,22 @@
+diff --git a/Makefile b/Makefile
+index 2f51bfc..395d6f1 100644
+--- a/Makefile
+++ b/Makefile
+@@ -1,7 +1,7 @@
+ CC=			gcc
+ CFLAGS=		-g -Wall -O2
+ #LDFLAGS=		-Wl,-rpath,\$$ORIGIN/../lib
+-DFLAGS=		-D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -D_USE_KNETFILE -D_CURSES_LIB=1
+DFLAGS=		-D_FILE_OFFSET_BITS=64 -D_LARGEFILE64_SOURCE -D_USE_KNETFILE # -D_CURSES_LIB=1
+ KNETFILE_O=	knetfile.o
+ LOBJS=		bgzf.o kstring.o bam_aux.o bam.o bam_import.o sam.o bam_index.o	\
+ 			bam_pileup.o bam_lpileup.o bam_md.o razf.o faidx.o bedidx.o \
+@@ -15,7 +15,7 @@ PROG=		samtools
+ INCLUDES=	-I.
+ SUBDIRS=	. bcftools misc
+ LIBPATH=
+-LIBCURSES=	-lcurses # -lXCurses
+LIBCURSES=	# -lcurses # -lXCurses
+ 
+ .SUFFIXES:.c .o
+ .PHONY: all lib
--- a/pkgs/applications/science/biology/samtools/samtools_0_1_19.nix
+++ b/pkgs/applications/science/biology/samtools/samtools_0_1_19.nix
@ -0,0 +1,33 @@
+{ lib, stdenv, fetchurl, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "samtools";
+  version = "0.1.19";
+
+  src = fetchurl {
+    url = "mirror://sourceforge/samtools/${pname}-${version}.tar.bz2";
+    sha256 = "d080c9d356e5f0ad334007e4461cbcee3c4ca97b8a7a5a48c44883cf9dee63d4";
+  };
+
+  patches = [
+    ./samtools-0.1.19-no-curses.patch
+  ];
+
+  buildInputs = [ zlib ];
+
+  installPhase = ''
+    mkdir -p $out/bin
+    mkdir -p $out/share/man
+
+    cp samtools $out/bin
+    cp samtools.1 $out/share/man
+  '';
+
+  meta = with lib; {
+    description = "Tools for manipulating SAM/BAM/CRAM format";
+    license = licenses.mit;
+    homepage = "http://samtools.sourceforge.net/";
+    platforms = platforms.unix;
+    maintainers = [ maintainers.unode ];
+  };
+}
--- a/pkgs/applications/science/biology/seaview/default.nix
+++ b/pkgs/applications/science/biology/seaview/default.nix
@ -0,0 +1,41 @@
+{ lib, stdenv, fetchurl, coreutils, fltk, libjpeg }:
+
+stdenv.mkDerivation rec {
+  version = "5.0.5";
+  pname = "seaview";
+
+  src = fetchurl {
+    url = "ftp://pbil.univ-lyon1.fr/pub/mol_phylogeny/seaview/archive/seaview_${version}.tar.gz";
+    sha256 = "sha256-zo9emLpHiDv6kekbx55NOibxWN2Zg7XngzGkUqSx+PI=";
+  };
+
+  buildInputs = [ fltk libjpeg ];
+
+  patchPhase = "sed -i 's#PATH=/bin:/usr/bin rm#'${coreutils}/bin/rm'#' seaview.cxx";
+  installPhase = "mkdir -p $out/bin; cp seaview $out/bin";
+
+  meta = with lib; {
+    description = "GUI for molecular phylogeny";
+    longDescription = ''
+      SeaView is a multiplatform, graphical user interface for multiple sequence alignment and molecular phylogeny.
+        - SeaView reads and writes various file formats (NEXUS, MSF, CLUSTAL, FASTA, PHYLIP, MASE, Newick) of DNA and protein sequences and of phylogenetic trees.
+        - SeaView drives programs muscle or Clustal Omega for multiple sequence alignment, and also allows to use any external alignment algorithm able to read and write FASTA-formatted files.
+        - Seaview drives the Gblocks program to select blocks of evolutionarily conserved sites.
+        - SeaView computes phylogenetic trees by
+          + parsimony, using PHYLIP's dnapars/protpars algorithm,
+          + distance, with NJ or BioNJ algorithms on a variety of evolutionary distances,
+          + maximum likelihood, driving program PhyML 3.1.
+        - Seaview can use the Transfer Bootstrap Expectation method to compute the bootstrap support of PhyML and distance trees.
+        - SeaView prints and draws phylogenetic trees on screen, SVG, PDF or PostScript files.
+        - SeaView allows to download sequences from EMBL/GenBank/UniProt using the Internet.
+
+      Seaview is published in:
+
+          Gouy M., Guindon S. & Gascuel O. (2010) SeaView version 4 : a multiplatform graphical user interface for sequence alignment and phylogenetic tree building. Molecular Biology and Evolution 27(2):221-224.
+    '';
+    homepage = "http://doua.prabi.fr/software/seaview";
+    license = licenses.gpl3;
+    maintainers = [ maintainers.iimog ];
+    platforms = platforms.linux;
+  };
+}
--- a/pkgs/applications/science/biology/snpeff/default.nix
+++ b/pkgs/applications/science/biology/snpeff/default.nix
@ -0,0 +1,35 @@
+{lib, stdenv, fetchurl, jre, unzip, makeWrapper}:
+
+stdenv.mkDerivation rec {
+  pname = "snpeff";
+  version = "4.3t";
+
+  src = fetchurl {
+    url = "mirror://sourceforge/project/snpeff/snpEff_v${builtins.replaceStrings [ "." ] [ "_" ] version}_core.zip";
+    sha256 = "0i12mv93bfv8xjwc3rs2x73d6hkvi7kgbbbx3ry984l3ly4p6nnm";
+  };
+
+  nativeBuildInputs = [ makeWrapper unzip ];
+  buildInputs = [ jre ];
+
+  sourceRoot = "snpEff";
+
+  installPhase = ''
+    mkdir -p $out/libexec/snpeff
+    cp *.jar *.config $out/libexec/snpeff
+
+    mkdir -p $out/bin
+    makeWrapper ${jre}/bin/java $out/bin/snpeff --add-flags "-jar $out/libexec/snpeff/snpEff.jar"
+    makeWrapper ${jre}/bin/java $out/bin/snpsift --add-flags "-jar $out/libexec/snpeff/SnpSift.jar"
+  '';
+
+  meta = with lib; {
+    description = "Genetic variant annotation and effect prediction toolbox";
+    license = licenses.lgpl3;
+    homepage = "http://snpeff.sourceforge.net/";
+    sourceProvenance = with sourceTypes; [ binaryBytecode ];
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.all;
+  };
+
+}
--- a/pkgs/applications/science/biology/somatic-sniper/default.nix
+++ b/pkgs/applications/science/biology/somatic-sniper/default.nix
@ -0,0 +1,29 @@
+{lib, stdenv, fetchFromGitHub, cmake, zlib, ncurses}:
+
+stdenv.mkDerivation rec {
+  pname = "somatic-sniper";
+  version = "1.0.5.0";
+
+  src = fetchFromGitHub {
+    owner = "genome";
+    repo = "somatic-sniper";
+    rev = "v${version}";
+    sha256 = "0lk7p9sp6mp50f6w1nppqhr40fcwy1asw06ivw8w8jvvnwaqf987";
+  };
+
+  patches = [ ./somatic-sniper.patch ];
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ zlib ncurses ];
+
+  enableParallelBuilding = false;
+
+  meta = with lib; {
+    description = "Identify single nucleotide positions that are different between tumor and normal";
+    license = licenses.mit;
+    homepage = "https://github.com/genome/somatic-sniper";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = platforms.linux;
+  };
+
+}
--- a/pkgs/applications/science/biology/somatic-sniper/somatic-sniper.patch
+++ b/pkgs/applications/science/biology/somatic-sniper/somatic-sniper.patch
@ -0,0 +1,26 @@
+diff --git a/CMakeLists.txt b/CMakeLists.txt
+index 6d5a180..7254292 100644
+--- a/CMakeLists.txt
+++ b/CMakeLists.txt
+@@ -11,7 +11,7 @@ set(CMAKE_MODULE_PATH
+     )
+ 
+ include(TestHelper)
+-include(VersionHelper)
+#include(VersionHelper)
+ include(ProjectHelper)
+ 
+ # NOTE: for sniper we want the exe suffix to be like 0.7.4, not just 0.7
+diff --git a/vendor/samtools.patch b/vendor/samtools.patch
+index f173017..654f878 100644
+--- a/vendor/samtools.patch
+++ b/vendor/samtools.patch
+@@ -6,7 +6,7 @@ diff -Nuar a/Makefile b/Makefile
+  
+  samtools:lib $(AOBJS)
+ -		$(CC) $(CFLAGS) -o $@ $(AOBJS) -lm $(LIBPATH) $(LIBCURSES) -lz -L. -lbam
+-+		$(CC) $(CFLAGS) -o $@ $(AOBJS) -lm $(LIBPATH) $(LIBCURSES) -L. -lbam -lz
++		$(CC) $(CFLAGS) -o $@ $(AOBJS) -lm $(LIBPATH) -lncurses -L. -lbam -lz
+  
+  razip:razip.o razf.o
+  		$(CC) $(CFLAGS) -o $@ razf.o razip.o -lz
--- a/pkgs/applications/science/biology/sortmerna/default.nix
+++ b/pkgs/applications/science/biology/sortmerna/default.nix
@ -0,0 +1,46 @@
+{ lib, stdenv, cmake, rocksdb, rapidjson, pkg-config, fetchFromGitHub, fetchpatch, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "sortmerna";
+  version = "4.2.0";
+
+  src = fetchFromGitHub {
+    repo = pname;
+    owner = "biocore";
+    rev = "v${version}";
+    sha256 = "0r91viylzr069jm7kpcgb45kagvf8sqcj5zc1af4arl9sgfs1f3j";
+  };
+
+  nativeBuildInputs = [ cmake pkg-config ];
+  buildInputs = [ zlib rocksdb rapidjson ];
+
+  cmakeFlags = [
+    "-DCMAKE_BUILD_TYPE=Release"
+    "-DPORTABLE=off"
+    "-DRAPIDJSON_HOME=${rapidjson}"
+    "-DROCKSDB_HOME=${rocksdb}"
+    "-DROCKSDB_STATIC=off"
+    "-DZLIB_STATIC=off"
+  ];
+
+  postPatch = ''
+    # Fix formatting string error:
+    # https://github.com/biocore/sortmerna/issues/255
+    substituteInPlace src/sortmerna/indexdb.cpp \
+      --replace 'is_verbose, ss' 'is_verbose, "%s", ss'
+
+    # Fix missing pthread dependency for the main binary.
+    substituteInPlace src/sortmerna/CMakeLists.txt \
+      --replace "target_link_libraries(sortmerna" \
+        "target_link_libraries(sortmerna Threads::Threads"
+  '';
+
+  meta = with lib; {
+    description = "Tools for filtering, mapping, and OTU-picking from shotgun genomics data";
+    license = licenses.lgpl3;
+    platforms = platforms.x86_64;
+    homepage = "https://bioinfo.lifl.fr/RNA/sortmerna/";
+    maintainers = with maintainers; [ luispedro ];
+    broken = stdenv.isDarwin;
+  };
+}
--- a/pkgs/applications/science/biology/spades/default.nix
+++ b/pkgs/applications/science/biology/spades/default.nix
@ -0,0 +1,27 @@
+{ lib, stdenv, fetchurl, zlib, bzip2, cmake, python3 }:
+
+stdenv.mkDerivation rec {
+  pname = "SPAdes";
+  version = "3.15.4";
+
+  src = fetchurl {
+    url = "http://cab.spbu.ru/files/release${version}/${pname}-${version}.tar.gz";
+    sha256 = "sha256-OyQcUopCqL398j5b+PAISDR5BZDQhJHezqnw8AnYWJ8=";
+  };
+
+  nativeBuildInputs = [ cmake ];
+
+  buildInputs = [ zlib bzip2 python3 ];
+
+  doCheck = true;
+
+  sourceRoot = "${pname}-${version}/src";
+
+  meta = with lib; {
+    description = "St. Petersburg genome assembler: assembly toolkit containing various assembly pipelines";
+    license = licenses.gpl2Only;
+    homepage = "http://cab.spbu.ru/software/spades/";
+    platforms = with platforms; [ "x86_64-linux" "x86_64-darwin"];
+    maintainers = [ maintainers.bzizou ];
+  };
+}
--- a/pkgs/applications/science/biology/stacks/default.nix
+++ b/pkgs/applications/science/biology/stacks/default.nix
@ -0,0 +1,19 @@
+{ lib, stdenv, fetchurl, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "stacks";
+  version = "2.60";
+  src = fetchurl {
+    url = "http://catchenlab.life.illinois.edu/stacks/source/${pname}-${version}.tar.gz";
+    sha256 = "sha256-ppKG7Z1TyLwUyqRnGYk3QWPJqKeNcW04GMW7myPFSNM=";
+  };
+
+  buildInputs = [ zlib ];
+
+  meta = {
+    description = "Software pipeline for building loci from short-read sequences";
+    homepage = "http://catchenlab.life.illinois.edu/stacks/";
+    maintainers = [ lib.maintainers.bzizou ];
+    license = lib.licenses.gpl3Plus;
+  };
+}
--- a/pkgs/applications/science/biology/star/default.nix
+++ b/pkgs/applications/science/biology/star/default.nix
@ -0,0 +1,39 @@
+{ lib, stdenv, fetchFromGitHub, zlib }:
+
+stdenv.mkDerivation rec {
+  pname = "star";
+  version = "2.7.10a";
+
+  src = fetchFromGitHub {
+    repo = "STAR";
+    owner = "alexdobin";
+    rev = version;
+    sha256 = "sha256-qwddCGMOKWgx76qGwRQXwvv9fCSeVsZbWHmlBwEqGKE=";
+  };
+
+  sourceRoot = "source/source";
+
+  postPatch = ''
+    substituteInPlace Makefile --replace "/bin/rm" "rm"
+  '';
+
+  buildInputs = [ zlib ];
+
+  buildFlags = [ "STAR" "STARlong" ];
+
+  enableParallelBuilding = true;
+
+  installPhase = ''
+    runHook preInstall
+    install -D STAR STARlong -t $out/bin
+    runHook postInstall
+  '';
+
+  meta = with lib; {
+    description = "Spliced Transcripts Alignment to a Reference";
+    homepage = "https://github.com/alexdobin/STAR";
+    license = licenses.gpl3Plus;
+    platforms = [ "x86_64-linux" ];
+    maintainers = [ maintainers.arcadio ];
+  };
+}
--- a/pkgs/applications/science/biology/strelka/default.nix
+++ b/pkgs/applications/science/biology/strelka/default.nix
@ -0,0 +1,43 @@
+{lib, stdenv, fetchFromGitHub, cmake, zlib, python2}:
+
+stdenv.mkDerivation rec {
+  pname = "strelka";
+  version = "2.9.10";
+
+  src = fetchFromGitHub {
+    owner = "Illumina";
+    repo = "strelka";
+    rev = "v${version}";
+    sha256 = "1nykbmim1124xh22nrhrsn8xgjb3s2y7akrdapn9sl1gdych4ppf";
+  };
+
+  nativeBuildInputs = [ cmake ];
+  buildInputs = [ zlib python2 ];
+
+  NIX_CFLAGS_COMPILE = [
+    "-Wno-error=maybe-uninitialized"
+    "-Wno-error=pessimizing-move"
+  ];
+
+  preConfigure = ''
+    sed -i 's|/usr/bin/env python|${python2}/bin/python|' src/python/lib/makeRunScript.py
+    patchShebangs .
+  '';
+
+  postFixup = ''
+    pushd $out/lib/python/pyflow
+    sed -i 's|/bin/bash|${stdenv.shell}|' pyflowTaskWrapper.py
+    rm pyflowTaskWrapper.pyc
+    echo "import pyflowTaskWrapper" | python2
+    popd
+  '';
+
+  meta = with lib; {
+    description = "Germline and small variant caller";
+    license = licenses.gpl3;
+    homepage = "https://github.com/Illumina/strelka";
+    maintainers = with maintainers; [ jbedo ];
+    platforms = [ "x86_64-linux" ];
+  };
+
+}
--- a/pkgs/applications/science/biology/subread/default.nix
+++ b/pkgs/applications/science/biology/subread/default.nix
@ -0,0 +1,41 @@
+{ lib
+, stdenv
+, fetchurl
+, zlib
+}:
+
+stdenv.mkDerivation rec {
+  pname = "subread";
+  version = "2.0.3";
+
+  src = fetchurl {
+    url = "mirror://sourceforge/subread/subread-${version}/subread-${version}-source.tar.gz";
+    sha256 = "sha256-Vs7zovkU1DJxMGnVwoL0iDHDoezIlDKtVYDKoyKl9Ws=";
+  };
+
+  buildInputs = [
+    zlib
+  ];
+
+  configurePhase = ''
+    cd src
+    cp Makefile.${if stdenv.isLinux then "Linux" else "MacOS"} Makefile
+  '';
+
+  makeFlags = [ "CC_EXEC=cc" ];
+
+  installPhase = ''
+    mkdir $out
+    cp -r ../bin $out
+  '';
+
+  meta = with lib; {
+    broken = stdenv.isDarwin;
+    description = "High-performance read alignment, quantification and mutation discovery";
+    license = licenses.gpl3;
+    maintainers = with maintainers; [ jbedo ];
+    platforms = [ "x86_64-darwin" "x86_64-linux" ];
+    homepage = "http://subread.sourceforge.net/";
+  };
+
+}
--- a/pkgs/applications/science/biology/sumatools/default.nix
+++ b/pkgs/applications/science/biology/sumatools/default.nix
@ -0,0 +1,68 @@
+{ lib, gccStdenv, fetchFromGitLab, zlib }:
+
+let
+  stdenv = gccStdenv;
+  meta = with lib; {
+    description = "Fast and exact comparison and clustering of sequences";
+    homepage = "https://metabarcoding.org/sumatra";
+    maintainers = [ maintainers.bzizou ];
+    platforms = platforms.unix;
+  };
+
+in rec {
+
+  # Suma library
+  sumalibs = stdenv.mkDerivation rec {
+    version = "1.0.34";
+    pname = "sumalibs";
+    src = fetchFromGitLab {
+      domain = "git.metabarcoding.org";
+      owner = "obitools";
+      repo = pname;
+      rev = "sumalib_v${version}";
+      sha256 = "0hwkrxzfz7m5wdjvmrhkjg8kis378iaqr5n4nhdhkwwhn8x1jn5a";
+    };
+    makeFlags = [ "PREFIX=$(out)" ];
+    inherit meta;
+  };
+
+  # Sumatra
+  sumatra = stdenv.mkDerivation rec {
+    version = "1.0.34";
+    pname = "sumatra";
+    src = fetchFromGitLab {
+      domain = "git.metabarcoding.org";
+      owner = "obitools";
+      repo = pname;
+      rev = "${pname}_v${version}";
+      sha256 = "1bbpbdkshdc3xffqnr1qfy8qk64ldsmdc3s8mrcrlx132rgbi5f6";
+    };
+    buildInputs = [ sumalibs zlib ];
+    makeFlags = [
+      "LIBSUMA=${sumalibs}/lib/libsuma.a"
+      "LIBSUMAPATH=-L${sumalibs}"
+      "PREFIX=$(out)"
+    ];
+    inherit meta;
+  };
+
+  # Sumaclust
+  sumaclust = stdenv.mkDerivation rec {
+    version = "1.0.34";
+    pname = "sumaclust";
+    src = fetchFromGitLab {
+      domain = "git.metabarcoding.org";
+      owner = "obitools";
+      repo = pname;
+      rev = "${pname}_v${version}";
+      sha256 = "0x8yi3k3jxhmv2krp4rcjlj2f9zg0qrk7gx4kpclf9c3yxgsgrds";
+    };
+    buildInputs = [ sumalibs ];
+    makeFlags = [
+      "LIBSUMA=${sumalibs}/lib/libsuma.a"
+      "LIBSUMAPATH=-L${sumalibs}"
+      "PREFIX=$(out)"
+    ];
+    inherit meta;
+  };
+}
--- a/Show more
+++ b/Show more